Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PCS91_RS08980 Genome accession   NZ_CP115365
Coordinates   1865998..1866654 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CUVET19-1426     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1860998..1871654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCS91_RS08935 (PCS91_08925) dcyD 1861100..1862086 (+) 987 WP_001565616.1 D-cysteine desulfhydrase -
  PCS91_RS08940 (PCS91_08930) tcyL 1862101..1862769 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PCS91_RS08945 (PCS91_08935) tcyN 1862766..1863518 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PCS91_RS08950 (PCS91_08940) sdiA 1863748..1864398 (+) 651 Protein_1748 transcriptional regulator SdiA -
  PCS91_RS08965 (PCS91_08955) yecF 1865315..1865539 (-) 225 WP_000106473.1 DUF2594 family protein YecF -
  PCS91_RS08970 (PCS91_08960) yecU 1865526..1865702 (-) 177 WP_000590344.1 protein YecU -
  PCS91_RS08975 - 1865740..1865856 (-) 117 WP_001302039.1 hypothetical protein -
  PCS91_RS08980 (PCS91_08965) letA 1865998..1866654 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PCS91_RS08985 (PCS91_08970) uvrC 1866651..1868483 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PCS91_RS08990 (PCS91_08975) pgsA 1868540..1869088 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PCS91_RS09010 (PCS91_08995) - 1869782..1870521 (-) 740 Protein_1756 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=703853 PCS91_RS08980 WP_000611328.1 1865998..1866654(+) (letA) [Escherichia coli strain CUVET19-1426]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=703853 PCS91_RS08980 WP_000611328.1 1865998..1866654(+) (letA) [Escherichia coli strain CUVET19-1426]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482