Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PCS94_RS09310 Genome accession   NZ_CP115351
Coordinates   1940347..1941003 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CUVET21-37     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1935347..1946003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCS94_RS09265 (PCS94_09260) dcyD 1935449..1936435 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  PCS94_RS09270 (PCS94_09265) tcyL 1936450..1937118 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PCS94_RS09275 (PCS94_09270) tcyN 1937115..1937867 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PCS94_RS09280 (PCS94_09275) - 1938097..1938429 (+) 333 Protein_1814 autoinducer binding domain-containing protein -
  PCS94_RS09285 (PCS94_09280) - 1938484..1939181 (+) 698 WP_223216371.1 IS1-like element IS1A family transposase -
  PCS94_RS09290 (PCS94_09285) sdiA 1939198..1939596 (+) 399 Protein_1816 transcriptional regulator SdiA -
  PCS94_RS09295 (PCS94_09290) yecF 1939664..1939888 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PCS94_RS09300 (PCS94_09295) yecU 1939875..1940051 (-) 177 WP_000590347.1 protein YecU -
  PCS94_RS09305 - 1940089..1940205 (-) 117 WP_001302039.1 hypothetical protein -
  PCS94_RS09310 (PCS94_09300) letA 1940347..1941003 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PCS94_RS09315 (PCS94_09305) uvrC 1941000..1942832 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PCS94_RS09320 (PCS94_09310) pgsA 1942889..1943437 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PCS94_RS09340 (PCS94_09330) yecA 1944087..1944752 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=703616 PCS94_RS09310 WP_000611335.1 1940347..1941003(+) (letA) [Escherichia coli strain CUVET21-37]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=703616 PCS94_RS09310 WP_000611335.1 1940347..1941003(+) (letA) [Escherichia coli strain CUVET21-37]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486