Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PCS96_RS01405 Genome accession   NZ_CP115330
Coordinates   289997..290653 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CUVET16-394     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 284997..295653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCS96_RS01375 (PCS96_01365) dcyD 285877..286863 (+) 987 WP_021561318.1 D-cysteine desulfhydrase -
  PCS96_RS01380 (PCS96_01370) tcyL 286878..287546 (+) 669 WP_001158231.1 cystine ABC transporter permease -
  PCS96_RS01385 (PCS96_01375) tcyN 287543..288295 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PCS96_RS01390 (PCS96_01380) sdiA 288525..289247 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  PCS96_RS01395 (PCS96_01385) yecF 289314..289538 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PCS96_RS01400 (PCS96_01390) yecU 289525..289701 (-) 177 WP_000590347.1 protein YecU -
  PCS96_RS01405 (PCS96_01395) letA 289997..290653 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PCS96_RS01410 (PCS96_01400) uvrC 290650..292482 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PCS96_RS01415 (PCS96_01405) pgsA 292539..293087 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PCS96_RS01435 (PCS96_01425) - 293794..294525 (-) 732 WP_001595862.1 hypothetical protein -
  PCS96_RS01440 (PCS96_01430) - 294606..295289 (+) 684 Protein_279 integrase arm-type DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=703333 PCS96_RS01405 WP_000611328.1 289997..290653(+) (letA) [Escherichia coli strain CUVET16-394]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=703333 PCS96_RS01405 WP_000611328.1 289997..290653(+) (letA) [Escherichia coli strain CUVET16-394]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482