Detailed information NTG0703270

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NHN23_RS04870
• Genome accession: NZ_CP099990
• Coordinates: 1021634..1022677 (+)
• Length: 347 a.a.
• NCBI ID: WP_002511392.1
• Uniprot ID: A0A9X4QYU5
• Organism: Staphylococcus equorum strain PU1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1016634..1027677

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NHN23_RS04845	-	1017691..1018410 (+)	720	WP_002507200.1	glutamine amidotransferase	-
NHN23_RS04850	-	1018509..1019495 (-)	987	WP_021339816.1	aromatic acid exporter family protein	-
NHN23_RS04855	map	1019676..1020428 (+)	753	WP_002507202.1	type I methionyl aminopeptidase	-
NHN23_RS04860	-	1020533..1020919 (+)	387	WP_002507203.1	hypothetical protein	-
NHN23_RS04865	liaF	1020936..1021637 (+)	702	WP_253345687.1	cell wall-active antibiotics response protein LiaF	-
NHN23_RS04870	vraS	1021634..1022677 (+)	1044	WP_002511392.1	sensor histidine kinase	Regulator
NHN23_RS04875	vraR	1022667..1023296 (+)	630	WP_002507206.1	response regulator transcription factor	Regulator
NHN23_RS04880	-	1023492..1024658 (-)	1167	WP_002511391.1	YihY/virulence factor BrkB family protein	-
NHN23_RS04885	-	1024889..1025173 (-)	285	WP_002507208.1	hypothetical protein	-
NHN23_RS04890	-	1025180..1025644 (-)	465	WP_002507209.1	low molecular weight protein-tyrosine-phosphatase	-
NHN23_RS04895	-	1025779..1025982 (+)	204	WP_002507210.1	DUF1128 family protein	-
NHN23_RS04900	-	1025998..1027236 (+)	1239	WP_064782814.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39973.32 Da
• Isoelectric Point: 5.8180

>NTDB_id=703270 NHN23_RS04870 WP_002511392.1 1021634..1022677(+) (vraS) [Staphylococcus equorum strain PU1]
MNHYIRAIGSMLILVYSTFFALFFIDKVFVNIVYFQGMFYTQIFGIPVLLFLNLLVIFLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEAPLDQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLKKKVPMKVVHDI
EEFEVPKGIEDHLFRITQEALSNTLRHSKGTKVTVELFNMADYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSHDD

Nucleotide

• Length: 1044 bp

>NTDB_id=703270 NHN23_RS04870 WP_002511392.1 1021634..1022677(+) (vraS) [Staphylococcus equorum strain PU1]
ATGAATCACTACATAAGAGCAATAGGATCCATGTTGATATTAGTTTATAGCACATTTTTTGCTCTGTTTTTTATCGATAA
AGTATTTGTAAACATAGTATATTTTCAAGGTATGTTTTATACACAAATTTTTGGAATACCAGTTTTACTATTTTTAAACT
TATTAGTTATTTTTCTTTGTATTATTGTAGGATCGGTATTAGCATATAAAATAAATCAACAAAATCACTGGTTACAAGAC
CAAATAGAACGTTCTATTGAAGGTCAAACAGTAGGTATTAATGATCAAAACATTGAATTATATAATGAAACAATTGAATT
GTATCAAACGTTAGTTCCATTAAATCAAGAAGTTCACAAATTACGTATGAAAACGCAAAACTTAACAAATGAATCATATA
ATATAAATGATGTGAAAGTTAAAAAGATTATAGAAGATGAACGACAAAGGCTTGCACGTGAATTACACGATTCAGTAAGT
CAGCAATTATTTGCAGCGAGTATGATGCTTTCAGCTATTAAAGAAACACAGTTAGAAGCACCTTTAGATCAACAAATTCC
GATATTAGAAAAAATGGTACAAGATTCTCAGTTAGAGATGAGAGCTTTACTATTACATTTAAGACCTATTGGATTAAAAG
ACAAATCATTAGGTGAAGGTATTAAAGATTTAGTCGTTGATTTAAAGAAAAAAGTACCTATGAAAGTTGTACATGATATT
GAAGAATTTGAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACGCAAGAAGCTTTATCTAATACTTTGAGACA
TTCAAAAGGTACCAAAGTAACAGTAGAATTGTTTAATATGGCAGATTACTTATTATTACGCATTCAAGACAATGGTAAAG
GGTTCAATGTTGATGATAAGGTAGAACAAAGTTATGGTTTAAAAAACATGAGAGAACGTGCGCTTGAAATTGGTGCAACG
TTTCATATTGTTTCTTTACCAGATTCAGGTACAAGAATTGAAGTAAAGGCACCATTAAATAAGGAGGATTCACATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.184	100	0.882