Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NG812_RS02145 Genome accession   NZ_CP099987
Coordinates   433283..433966 (+) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae strain FUA009     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 428283..438966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NG812_RS02135 (NG812_02125) rpoC 428391..432038 (+) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -
  NG812_RS02140 (NG812_02130) - 432131..433039 (-) 909 WP_165705977.1 diacylglycerol kinase family protein -
  NG812_RS02145 (NG812_02135) mecA 433283..433966 (+) 684 WP_004259224.1 adaptor protein MecA Regulator
  NG812_RS02150 (NG812_02140) - 433970..435226 (+) 1257 WP_074750514.1 glycosyltransferase family 4 protein -
  NG812_RS02155 (NG812_02145) sufC 435304..436074 (+) 771 WP_014024332.1 Fe-S cluster assembly ATPase SufC -
  NG812_RS02160 (NG812_02150) sufD 436146..437402 (+) 1257 WP_019299087.1 Fe-S cluster assembly protein SufD -
  NG812_RS02165 (NG812_02155) - 437402..438613 (+) 1212 WP_165705975.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=703189 NG812_RS02145 WP_004259224.1 433283..433966(+) (mecA) [Lactococcus garvieae strain FUA009]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=703189 NG812_RS02145 WP_004259224.1 433283..433966(+) (mecA) [Lactococcus garvieae strain FUA009]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCGATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAACTGGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACCGAGGAAAATATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCTGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCCGT
AAGTTCGATGCGTGCCCGAATGTTAGAATATGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555