Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DOM77_RS05620 Genome accession   NZ_AP018676
Coordinates   1124159..1126000 (+) Length   613 a.a.
NCBI ID   WP_172586718.1    Uniprot ID   -
Organism   Helicobacter cinaedi strain P01D0000     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1119159..1131000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DOM77_RS05590 mog 1119575..1120105 (+) 531 WP_014666653.1 molybdopterin adenylyltransferase -
  DOM77_RS05595 moaC 1120127..1120603 (+) 477 WP_104716681.1 cyclic pyranopterin monophosphate synthase MoaC -
  DOM77_RS05600 rmuC 1120613..1121956 (+) 1344 WP_104716682.1 DNA recombination protein RmuC -
  DOM77_RS05605 nadB 1121971..1123416 (-) 1446 WP_104716683.1 L-aspartate oxidase -
  DOM77_RS05610 - 1123417..1123665 (-) 249 WP_002956815.1 hypothetical protein -
  DOM77_RS05615 - 1123657..1124115 (+) 459 WP_231900552.1 hypothetical protein -
  DOM77_RS05620 uvrC 1124159..1126000 (+) 1842 WP_172586718.1 excinuclease ABC subunit UvrC Machinery gene
  DOM77_RS05625 - 1125997..1127478 (+) 1482 WP_014666647.1 hypothetical protein -
  DOM77_RS05630 - 1127488..1129044 (+) 1557 WP_109204987.1 sensor histidine kinase -
  DOM77_RS05635 - 1129047..1129736 (+) 690 WP_002956820.1 response regulator -

Sequence

Protein


Download         Length: 613 a.a.        Molecular weight: 70757.33 Da        Isoelectric Point: 9.7723

>NTDB_id=70255 DOM77_RS05620 WP_172586718.1 1124159..1126000(+) (uvrC) [Helicobacter cinaedi strain P01D0000]
MYSLLFTLQNLPTQPGIYQYFDKDDNLLYVGKAKNLKNRIKSYFSIHNDIITPKANLSQRIALMVSQVAKIHTLLTQNQE
DALILENSLIKSLKPKYNILLRDDKTYPYIYIDTSATFPRFEITRKVLQSKHIEYFGPFVSGARELLDSLYDALPLVQKK
SCLKGKKACIFHQIHKCPAPCENKISQSQYAEYITQAKAFIDDRKGLIEILESKMQILSHNLQFEEAAKIRDRIQKLKTL
KTQSIIDIMSGDYDIFLLDSAGQNHILMMLFIRNGRIVSSDFSFIHQEIHSQNLAQLYTQALLNHYKTPLPLPPKEILIP
HFDFQDKDEKDDLQKILQAQTQSHLKITQPQKGTKYNLLQLAKKNAQEILTLHTKEQKNAQNENTTLYALKDLCNLSQVP
YRIEIFDTSHHSGSHNVGGMVVYENGEFIRSAYRRFELHSSDEYSQMSEMLTRRAKKFESNPPPDLWLLDGGKAQINLAL
DILKSVGANVDIIAIAKMKYNAKAYRAKGNALDILRTQNAEFKLSTNDKRLQFCQKLRDEVHRYAITYHRNKKQKDIHKI
QIQKGSDMDSSYSKAQIKRLLDYFGSFHAIQNAPKEQIENALSRSFKSNKDSK

Nucleotide


Download         Length: 1842 bp        

>NTDB_id=70255 DOM77_RS05620 WP_172586718.1 1124159..1126000(+) (uvrC) [Helicobacter cinaedi strain P01D0000]
ATATATAGTCTGCTTTTTACCCTGCAAAATCTCCCTACACAGCCCGGAATCTACCAATATTTTGATAAAGATGATAACTT
GCTCTATGTCGGCAAGGCTAAAAATCTAAAAAATCGCATAAAAAGCTATTTTTCTATCCATAATGACATCATCACGCCAA
AGGCTAACCTTAGCCAAAGAATAGCCCTTATGGTATCCCAAGTGGCTAAGATTCACACTTTACTTACACAAAACCAAGAA
GATGCCCTTATCCTTGAAAACTCCCTTATCAAAAGCCTAAAGCCAAAGTATAATATTCTTTTGCGTGATGATAAAACTTA
TCCTTATATTTATATTGATACTTCTGCTACTTTTCCACGATTTGAAATCACTCGCAAGGTGCTACAAAGTAAGCATATTG
AGTATTTTGGTCCTTTTGTGAGTGGAGCTAGAGAGCTGCTTGATAGTCTCTATGATGCCCTGCCCCTTGTGCAGAAAAAA
TCCTGCCTTAAAGGCAAAAAGGCGTGTATATTTCATCAGATTCATAAATGCCCTGCCCCTTGTGAAAATAAAATCTCTCA
AAGTCAATATGCAGAGTATATTACACAAGCAAAGGCGTTTATAGATGATAGAAAAGGACTTATAGAGATTTTAGAATCTA
AAATGCAGATACTCTCACACAATTTACAATTTGAAGAGGCAGCAAAGATACGAGATAGAATCCAAAAGCTAAAAACACTA
AAAACCCAATCTATTATTGATATTATGAGCGGAGATTATGATATTTTCCTGCTTGATTCAGCAGGGCAAAATCATATCCT
TATGATGCTTTTTATCCGCAATGGACGCATTGTCTCAAGTGATTTTTCATTTATCCACCAAGAGATTCACAGCCAAAACC
TAGCCCAACTCTACACCCAAGCCTTACTTAATCACTATAAAACCCCTCTTCCCTTGCCACCAAAGGAGATTCTTATCCCG
CATTTTGACTTCCAAGACAAAGATGAAAAAGATGATTTACAAAAGATTTTGCAAGCCCAAACACAAAGTCATCTCAAAAT
CACCCAACCACAAAAAGGCACAAAATATAACCTTTTGCAACTTGCTAAAAAGAACGCCCAAGAAATCCTAACTTTGCATA
CCAAAGAGCAAAAGAACGCCCAAAATGAAAACACCACTTTATACGCTCTAAAAGATTTATGCAATCTCTCTCAAGTGCCT
TATAGGATAGAGATCTTTGACACCTCTCATCATAGCGGAAGCCACAATGTAGGCGGAATGGTAGTGTATGAAAATGGCGA
GTTTATCCGCAGTGCTTACAGACGCTTTGAGCTTCATAGCAGTGATGAATACTCTCAAATGAGTGAAATGCTAACACGCA
GGGCAAAAAAATTTGAATCCAATCCGCCACCAGATTTATGGCTACTTGATGGGGGCAAGGCTCAAATCAACCTAGCACTT
GACATTCTAAAAAGTGTGGGGGCAAATGTAGATATTATCGCCATTGCCAAAATGAAATATAATGCCAAAGCCTATCGCGC
TAAAGGCAATGCCCTTGATATTTTACGCACACAAAATGCGGAGTTTAAACTTAGCACAAACGATAAAAGACTACAATTCT
GCCAAAAGCTCCGCGATGAAGTGCATAGATATGCTATCACTTATCATCGCAACAAAAAGCAAAAAGACATACACAAGATT
CAGATTCAAAAAGGAAGTGATATGGATAGCTCTTATAGCAAGGCTCAAATTAAACGACTTTTAGATTATTTTGGCTCATT
CCACGCCATTCAAAACGCTCCAAAAGAACAGATAGAAAATGCTCTTTCACGCTCTTTTAAAAGTAATAAAGATTCAAAAT
GA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(207-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(392-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.244

98.369

0.504

Multiple sequence alignment