Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL289_RS05065 Genome accession   NZ_AP018586
Coordinates   1070882..1071511 (+) Length   209 a.a.
NCBI ID   WP_037541848.1    Uniprot ID   -
Organism   Staphylococcus caprae strain JMUB590     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1065882..1076511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL289_RS05035 (JMUB590_1014) isaB 1065978..1066529 (+) 552 WP_002445468.1 immunodominant staphylococcal antigen IsaB family protein -
  EL289_RS05040 (JMUB590_1015) - 1066673..1067662 (-) 990 WP_002445470.1 FUSC family protein -
  EL289_RS05045 (JMUB590_1016) map 1067837..1068592 (+) 756 WP_002445472.1 type I methionyl aminopeptidase -
  EL289_RS05050 (JMUB590_1017) - 1068747..1069133 (+) 387 WP_002445473.1 hypothetical protein -
  EL289_RS05055 (JMUB590_1018) liaF 1069148..1069849 (+) 702 WP_002445474.1 cell wall-active antibiotics response protein LiaF -
  EL289_RS05060 (JMUB590_1019) vraS 1069846..1070892 (+) 1047 WP_002445475.1 sensor histidine kinase Regulator
  EL289_RS05065 (JMUB590_1020) vraR 1070882..1071511 (+) 630 WP_037541848.1 two-component system response regulator VraR Regulator
  EL289_RS05070 (JMUB590_1021) - 1071572..1072828 (-) 1257 WP_002445478.1 YihY/virulence factor BrkB family protein -
  EL289_RS05075 (JMUB590_1022) - 1073201..1073485 (-) 285 WP_002445480.1 hypothetical protein -
  EL289_RS05080 (JMUB590_1023) - 1073491..1073955 (-) 465 WP_002445482.1 low molecular weight protein-tyrosine-phosphatase -
  EL289_RS05085 (JMUB590_1024) - 1074096..1074302 (+) 207 WP_002445484.1 DUF1128 domain-containing protein -
  EL289_RS05090 (JMUB590_1025) - 1074315..1075553 (+) 1239 WP_002445487.1 aminopeptidase -
  EL289_RS05095 (JMUB590_1026) - 1075665..1076195 (+) 531 WP_002445489.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23632.28 Da        Isoelectric Point: 4.8156

>NTDB_id=70163 EL289_RS05065 WP_037541848.1 1070882..1071511(+) (vraR) [Staphylococcus caprae strain JMUB590]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAIEKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYQGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=70163 EL289_RS05065 WP_037541848.1 1070882..1071511(+) (vraR) [Staphylococcus caprae strain JMUB590]
ATGGCGATTAAAGTATTATTTGTGGATGATCACGAAATGGTTAGAATAGGTATTTCTAGTTATCTTTCTACACAAGAAGA
TATTGAGGTAGTAGGCGAGGGTGCTTCAGGAAAAGAAGCCATTGAGAAAGCACACGAATTAAAGCCAGATTTAATTTTAA
TGGACCTACTGATGGACGATATGGATGGTGTAGAAGCCACAACCGAAATAAAAAAGGATTTACCTCATATTAAAGTCGTG
ATGTTAACAAGCTTTATTGAAGATAAAGAAGTTTATCGTGCGTTAGATGCCGGTGTAGATAGTTATATTTTAAAAACAAC
AAGCGCAAGTGATATTGCTGAAGCAGTACGTAAAACATATCAAGGTGAATCAGTGTTTGAACCTGAAGTACTTGTGAAAA
TGAGAAATCGAATGAAAAAACGTGCGGAATTATATGAAATGTTAACAGAACGTGAAATGGAAATCTTATTATTAATCGCA
AAAGGGTATTCAAATCAAGAAATTGCGAGTGCATCTCATATTACAATTAAAACTGTTAAAACGCATGTGAGTAATATTCT
AAGTAAATTAGAAGTACAAGATAGAACACAAGCTGTTATCTATGCTTTCCAACACAATCTTATACAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment