Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NEE09_RS09245 Genome accession   NZ_CP099641
Coordinates   1788133..1788822 (-) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain ATCC 700671     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1783133..1793822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NEE09_RS09220 - 1783807..1784136 (-) 330 WP_000619581.1 transposase -
  NEE09_RS09225 - 1784799..1785157 (+) 359 Protein_1774 lantibiotic-modifying protein -
  NEE09_RS09230 - 1785057..1785527 (+) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  NEE09_RS09235 - 1785686..1786918 (+) 1233 WP_000765684.1 MFS transporter -
  NEE09_RS09240 cbpJ 1787036..1788034 (-) 999 WP_000771053.1 choline-binding protein CbpJ -
  NEE09_RS09245 covR 1788133..1788822 (-) 690 WP_000518008.1 response regulator transcription factor Regulator
  NEE09_RS09250 gndA 1788834..1790258 (-) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  NEE09_RS09255 mapZ 1790334..1791728 (-) 1395 WP_000039255.1 mid-cell-anchored protein MapZ -
  NEE09_RS09260 - 1791741..1792898 (-) 1158 WP_000711414.1 class I SAM-dependent RNA methyltransferase -
  NEE09_RS09270 gpsB 1793384..1793725 (-) 342 WP_000200645.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=701225 NEE09_RS09245 WP_000518008.1 1788133..1788822(-) (covR) [Streptococcus pneumoniae strain ATCC 700671]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=701225 NEE09_RS09245 WP_000518008.1 1788133..1788822(-) (covR) [Streptococcus pneumoniae strain ATCC 700671]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCAATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467