Detailed information NTG0701179

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NEE09_RS01700
• Genome accession: NZ_CP099641
• Coordinates: 316443..317480 (+)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ATCC 700671
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 311443..322480

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NEE09_RS01665	yidC	311478..312404 (-)	927	WP_000835955.1	membrane protein insertase YidC	-
NEE09_RS01670	-	312482..312760 (-)	279	WP_001174614.1	acylphosphatase	-
NEE09_RS01675	-	312794..313534 (+)	741	WP_000152679.1	RNA methyltransferase	-
NEE09_RS01680	-	313590..314273 (+)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
NEE09_RS01685	asnA	314385..315377 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
NEE09_RS01690	rsmD	315442..315981 (+)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NEE09_RS01695	coaD	315971..316459 (+)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
NEE09_RS01700	sepM	316443..317480 (+)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
NEE09_RS01705	-	317538..317768 (+)	231	WP_000250390.1	DUF1146 family protein	-
NEE09_RS01710	murA	317792..319075 (+)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
NEE09_RS01715	-	319068..319256 (+)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
NEE09_RS01720	endA	319295..320119 (+)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
NEE09_RS01725	-	320410..321741 (+)	1332	WP_000390042.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=701179 NEE09_RS01700 WP_001813016.1 316443..317480(+) (sepM) [Streptococcus pneumoniae strain ATCC 700671]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=701179 NEE09_RS01700 WP_001813016.1 316443..317480(+) (sepM) [Streptococcus pneumoniae strain ATCC 700671]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588