Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   NEE09_RS01720 Genome accession   NZ_CP099641
Coordinates   319295..320119 (+) Length   274 a.a.
NCBI ID   WP_001036791.1    Uniprot ID   A0A0B7L7Z9
Organism   Streptococcus pneumoniae strain ATCC 700671     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 314295..325119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NEE09_RS01685 asnA 314385..315377 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  NEE09_RS01690 rsmD 315442..315981 (+) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  NEE09_RS01695 coaD 315971..316459 (+) 489 WP_001280746.1 pantetheine-phosphate adenylyltransferase -
  NEE09_RS01700 sepM 316443..317480 (+) 1038 WP_001813016.1 SepM family pheromone-processing serine protease Regulator
  NEE09_RS01705 - 317538..317768 (+) 231 WP_000250390.1 DUF1146 family protein -
  NEE09_RS01710 murA 317792..319075 (+) 1284 WP_000358032.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  NEE09_RS01715 - 319068..319256 (+) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  NEE09_RS01720 endA 319295..320119 (+) 825 WP_001036791.1 DNA-entry nuclease EndA Machinery gene
  NEE09_RS01725 - 320410..321741 (+) 1332 WP_000390042.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29939.65 Da        Isoelectric Point: 10.1700

>NTDB_id=701180 NEE09_RS01720 WP_001036791.1 319295..320119(+) (endA) [Streptococcus pneumoniae strain ATCC 700671]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=701180 NEE09_RS01720 WP_001036791.1 319295..320119(+) (endA) [Streptococcus pneumoniae strain ATCC 700671]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7L7Z9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.54

100

0.985
  endA Streptococcus pneumoniae D39

98.54

100

0.985
  endA Streptococcus pneumoniae R6

98.54

100

0.985
  endA Streptococcus pneumoniae TIGR4

98.54

100

0.985