Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   NHB12_RS10810 Genome accession   NZ_CP099576
Coordinates   2154688..2155404 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain MRSA1369     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2149688..2160404
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NHB12_RS10780 (NHB12_10780) - 2149907..2150533 (+) 627 WP_000522384.1 nitroreductase family protein -
  NHB12_RS10785 (NHB12_10785) - 2150894..2151679 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  NHB12_RS14605 - 2152276..2152410 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  NHB12_RS10795 (NHB12_10795) agrB 2152646..2153215 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  NHB12_RS10800 (NHB12_10800) agrD 2153212..2153352 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  NHB12_RS10805 (NHB12_10805) agrC 2153377..2154669 (+) 1293 WP_001549202.1 quorum-sensing sensor histidine kinase AgrC -
  NHB12_RS10810 (NHB12_10810) agrA 2154688..2155404 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  NHB12_RS10815 (NHB12_10815) - 2155476..2155583 (+) 108 WP_001790167.1 hypothetical protein -
  NHB12_RS10820 (NHB12_10820) - 2155771..2156730 (-) 960 WP_001253312.1 carbohydrate kinase -
  NHB12_RS10825 (NHB12_10825) - 2156727..2158211 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  NHB12_RS10830 (NHB12_10830) - 2158360..2159310 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=700800 NHB12_RS10810 WP_000688492.1 2154688..2155404(+) (agrA) [Staphylococcus aureus strain MRSA1369]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=700800 NHB12_RS10810 WP_000688492.1 2154688..2155404(+) (agrA) [Staphylococcus aureus strain MRSA1369]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1