Detailed information NTG0069977

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SA27298_RS03690
• Genome accession: NZ_AP018548
• Coordinates: 755499..756731 (+)
• Length: 410 a.a.
• NCBI ID: WP_003027977.1
• Uniprot ID: I0SHV1
• Organism: Streptococcus anginosus strain CCUG 27928
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 750499..761731

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA27298_RS03665 (SA27298_0751)	-	752165..752431 (+)	267	WP_003032250.1	chorismate mutase	-
SA27298_RS03670 (SA27298_0752)	-	752446..753663 (+)	1218	WP_003032253.1	chloride channel protein	-
SA27298_RS03675 (SA27298_0753)	-	753749..754588 (+)	840	WP_003032264.1	thymidylate synthase	-
SA27298_RS03680 (SA27298_0755)	-	754775..755287 (+)	513	WP_003032260.1	dihydrofolate reductase	-
SA27298_RS03685 (SA27298_0756)	-	755287..755460 (+)	174	WP_003032252.1	hypothetical protein	-
SA27298_RS03690 (SA27298_0757)	clpX	755499..756731 (+)	1233	WP_003027977.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SA27298_RS03695 (SA27298_0758)	yihA	756743..757330 (+)	588	WP_003032247.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SA27298_RS03700 (SA27298_0759)	-	757451..758158 (+)	708	WP_003032270.1	glucosaminidase domain-containing protein	-
SA27298_RS03705 (SA27298_0760)	-	758331..760076 (+)	1746	WP_003032265.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45688.21 Da
• Isoelectric Point: 4.4242

>NTDB_id=69977 SA27298_RS03690 WP_003027977.1 755499..756731(+) (clpX) [Streptococcus anginosus strain CCUG 27928]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNREDEEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=69977 SA27298_RS03690 WP_003027977.1 755499..756731(+) (clpX) [Streptococcus anginosus strain CCUG 27928]
ATGCCTACAAATCGTACGAACGAAATGATGGTTTATTGTTCTTTTTGTGGTAAAAGCCAAGAGGAAGTTCAAAAAATTAT
CGCAGGAAATAATGCCTTCATTTGTAATGAATGTGTGGAATTAGCACAAGAAATTATTAGAGAAGAATTGGCAGAAGAAG
TGCTGGCAGACTTGTCAGAAGTACCAAAACCGCAAGAACTACTCAATATTTTGAATCATTATGTGATTGGACAAGACCGT
GCTAAGCGAGCATTGGCCGTTGCTGTTTACAATCACTATAAACGCATCAATTTTCATGATAATCGTGAAGATGAGGAAGA
TGTCGAATTGCAGAAATCCAATATCCTCATGATTGGGCCAACTGGTTCTGGCAAGACCTTTCTCGCTCAAACTTTGGCAA
AAAGTCTGAATGTTCCTTTTGCGATTGCAGATGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCTGAACGTGGTATCATCTATGTAGATGAGATTGA
TAAAATTGCGAAGAAAAGCGAAAATGTCTCTATTACTCGTGATGTGTCTGGTGAAGGTGTTCAGCAAGCGCTCCTCAAAA
TTATTGAAGGAACAGTAGCCAGCGTACCTCCGCAAGGCGGCCGCAAGCACCCTCAACAAGAGATGATTCAAGTAGATACG
AAAAATATTCTCTTTATCGTTGGTGGTGCATTTGACGGTATTGAAGAAATTGTCAAACAACGTCTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAACAACAAGGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGCTTGATTCCGGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTAACAGTTGATGATTTGGTGCGA
ATCCTTCGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTTCTTTCTTATGATGATGTCAAATTGGAGTTTGA
TGATGATGCTCTCCAAGAGATTGCCAACAAAGCCATTGAACGTAAGACAGGTGCGCGTGGATTGCGGTCGATTATCGAGG
AAACTATGATGGATGTCATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGTTAGTGCGGATTACCAAGGAAGCAGTTGAC
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

3D structure

• AlphaFold DB: I0SHV1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.829	100	0.868
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.458	98.049	0.573