Detailed information
Bioinformatically predicted
Overview
| Name | comE | Type | Machinery gene |
| Locus tag | NDQ64_RS08480 | Genome accession | NZ_CP098544 |
| Coordinates | 1612607..1613002 (-) | Length | 131 a.a. |
| NCBI ID | WP_003703428.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain 10296 | ||
| Function | DNA binding (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1579789..1611821 | 1612607..1613002 | flank | 786 |
Gene organization within MGE regions
Location: 1579789..1613002
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NDQ64_RS08225 (NDQ64_08130) | - | 1579817..1580791 (-) | 975 | WP_003689550.1 | SIS domain-containing protein | - |
| NDQ64_RS08230 (NDQ64_08135) | tal | 1580888..1581943 (+) | 1056 | WP_003695503.1 | transaldolase | - |
| NDQ64_RS08235 | - | 1581955..1582089 (+) | 135 | WP_012503902.1 | hypothetical protein | - |
| NDQ64_RS08240 (NDQ64_08140) | - | 1582094..1582384 (+) | 291 | WP_003689553.1 | hypothetical protein | - |
| NDQ64_RS08245 (NDQ64_08145) | gluQRS | 1582401..1583288 (+) | 888 | WP_003689554.1 | tRNA glutamyl-Q(34) synthetase GluQRS | - |
| NDQ64_RS08250 (NDQ64_08150) | dusA | 1583358..1584374 (-) | 1017 | WP_003689555.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
| NDQ64_RS08255 (NDQ64_08155) | - | 1584494..1585648 (+) | 1155 | WP_003693486.1 | tyrosine-type recombinase/integrase | - |
| NDQ64_RS08260 (NDQ64_08160) | - | 1585698..1585964 (-) | 267 | WP_003689557.1 | pyocin activator PrtN family protein | - |
| NDQ64_RS08265 (NDQ64_08165) | - | 1586072..1587220 (-) | 1149 | WP_003705649.1 | hypothetical protein | - |
| NDQ64_RS08270 (NDQ64_08170) | - | 1587217..1588200 (-) | 984 | WP_260244315.1 | hypothetical protein | - |
| NDQ64_RS08275 (NDQ64_08175) | - | 1588311..1588526 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| NDQ64_RS08280 (NDQ64_08180) | - | 1588578..1589069 (-) | 492 | WP_047918703.1 | siphovirus Gp157 family protein | - |
| NDQ64_RS08285 (NDQ64_08185) | - | 1589066..1589248 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| NDQ64_RS08290 (NDQ64_08190) | - | 1589388..1590074 (-) | 687 | WP_010951053.1 | phage replication initiation protein, NGO0469 family | - |
| NDQ64_RS08295 (NDQ64_08195) | - | 1590143..1590304 (-) | 162 | WP_003702497.1 | hypothetical protein | - |
| NDQ64_RS08300 (NDQ64_08200) | - | 1590301..1590579 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| NDQ64_RS08305 (NDQ64_08205) | - | 1590732..1591064 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| NDQ64_RS08310 (NDQ64_08210) | - | 1591205..1591510 (-) | 306 | WP_260244314.1 | hypothetical protein | - |
| NDQ64_RS08315 (NDQ64_08215) | - | 1591507..1591983 (-) | 477 | WP_012504141.1 | DUF6948 domain-containing protein | - |
| NDQ64_RS08320 (NDQ64_08220) | - | 1592016..1592216 (-) | 201 | WP_003704298.1 | hypothetical protein | - |
| NDQ64_RS08325 (NDQ64_08225) | - | 1592700..1592918 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| NDQ64_RS08330 (NDQ64_08230) | - | 1592935..1593294 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| NDQ64_RS08335 (NDQ64_08235) | - | 1593295..1593834 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| NDQ64_RS08340 (NDQ64_08240) | - | 1593994..1594710 (-) | 717 | WP_003695999.1 | helix-turn-helix transcriptional regulator | - |
| NDQ64_RS08345 (NDQ64_08245) | - | 1595091..1595318 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| NDQ64_RS08350 (NDQ64_08250) | - | 1595436..1596500 (+) | 1065 | WP_003689134.1 | hypothetical protein | - |
| NDQ64_RS08355 (NDQ64_08255) | - | 1596497..1597858 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| NDQ64_RS08360 (NDQ64_08260) | - | 1597875..1598105 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| NDQ64_RS08365 (NDQ64_08265) | - | 1598196..1598690 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| NDQ64_RS08370 (NDQ64_08270) | - | 1599074..1599223 (+) | 150 | WP_106278816.1 | hypothetical protein | - |
| NDQ64_RS08375 (NDQ64_08275) | - | 1599252..1599533 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NDQ64_RS08380 (NDQ64_08280) | - | 1599524..1599904 (+) | 381 | WP_033910829.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NDQ64_RS08385 | - | 1599921..1600049 (-) | 129 | WP_012503747.1 | hypothetical protein | - |
| NDQ64_RS08390 (NDQ64_08285) | - | 1600233..1601195 (-) | 963 | WP_057330785.1 | IS110 family transposase | - |
| NDQ64_RS08395 (NDQ64_08290) | - | 1601708..1602067 (-) | 360 | WP_003689732.1 | hypothetical protein | - |
| NDQ64_RS08400 (NDQ64_08295) | - | 1602188..1603260 (-) | 1073 | Protein_1627 | zonular occludens toxin domain-containing protein | - |
| NDQ64_RS08405 (NDQ64_08300) | - | 1603270..1603560 (-) | 291 | WP_012503936.1 | DUF2523 domain-containing protein | - |
| NDQ64_RS08410 (NDQ64_08305) | - | 1603539..1605128 (-) | 1590 | WP_260244331.1 | IgG-binding virulence factor TspB family protein | - |
| NDQ64_RS08415 (NDQ64_08310) | - | 1605070..1605387 (-) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| NDQ64_RS08420 (NDQ64_08315) | - | 1605515..1605793 (-) | 279 | WP_003691583.1 | hypothetical protein | - |
| NDQ64_RS08425 (NDQ64_08320) | - | 1605800..1606018 (-) | 219 | WP_003691584.1 | major capsid protein | - |
| NDQ64_RS08430 (NDQ64_08325) | - | 1606092..1606289 (-) | 198 | WP_003689600.1 | hypothetical protein | - |
| NDQ64_RS08435 (NDQ64_08330) | - | 1606294..1606584 (-) | 291 | WP_012503914.1 | hypothetical protein | - |
| NDQ64_RS08440 (NDQ64_08335) | - | 1606629..1607978 (-) | 1350 | WP_025455830.1 | replication initiation factor domain-containing protein | - |
| NDQ64_RS08445 (NDQ64_08340) | - | 1608117..1608539 (-) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| NDQ64_RS08450 (NDQ64_08345) | - | 1608545..1609141 (-) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| NDQ64_RS08455 (NDQ64_08350) | - | 1609331..1610188 (-) | 858 | WP_012503917.1 | ATP-binding protein | - |
| NDQ64_RS08460 (NDQ64_08355) | - | 1610202..1610573 (-) | 372 | WP_012503918.1 | DNA cytosine methyltransferase | - |
| NDQ64_RS08465 (NDQ64_08360) | - | 1610570..1611178 (-) | 609 | WP_080229275.1 | DNA cytosine methyltransferase | - |
| NDQ64_RS08470 (NDQ64_08365) | - | 1611547..1611693 (+) | 147 | WP_003691757.1 | hypothetical protein | - |
| NDQ64_RS08475 (NDQ64_08370) | comP | 1612070..1612519 (-) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
| NDQ64_RS08480 (NDQ64_08375) | comE | 1612607..1613002 (-) | 396 | WP_003703428.1 | helix-hairpin-helix domain-containing protein | Machinery gene |
Sequence
Protein
Download Length: 131 a.a. Molecular weight: 13796.61 Da Isoelectric Point: 10.8790
>NTDB_id=696886 NDQ64_RS08480 WP_003703428.1 1612607..1613002(-) (comE) [Neisseria gonorrhoeae strain 10296]
MSRGGATPYRFLLIRHIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINAASQQELEALPGIGPAKAKAIAEY
RAQNGAFKSVDDLIKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPAVKK
MSRGGATPYRFLLIRHIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINAASQQELEALPGIGPAKAKAIAEY
RAQNGAFKSVDDLIKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPAVKK
Nucleotide
Download Length: 396 bp
>NTDB_id=696886 NDQ64_RS08480 WP_003703428.1 1612607..1613002(-) (comE) [Neisseria gonorrhoeae strain 10296]
TTGAGCCGGGGCGGGGCAACGCCGTACCGGTTTTTGTTAATCCGCCATATCGTCGCAAGATGCGGTTTGTTGTTTGCAAC
CCTTAAAGGAAAAACCATGAAAAAAATGTTTGTATTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAA
ACATCAATGCGGCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATAC
CGCGCGCAAAACGGCGCGTTCAAGTCTGTGGACGATTTGATCAAGGTGAAGGGCATCGGTCCGGCGGTGCTGGCGAAGCT
GAAAGACCAGGCTTCCGTCGGCGCGCCCGCACCAAAAGGCCCCGCCAAACCGGTGCTGCCTGCGGTTAAAAAATAG
TTGAGCCGGGGCGGGGCAACGCCGTACCGGTTTTTGTTAATCCGCCATATCGTCGCAAGATGCGGTTTGTTGTTTGCAAC
CCTTAAAGGAAAAACCATGAAAAAAATGTTTGTATTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAA
ACATCAATGCGGCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATAC
CGCGCGCAAAACGGCGCGTTCAAGTCTGTGGACGATTTGATCAAGGTGAAGGGCATCGGTCCGGCGGTGCTGGCGAAGCT
GAAAGACCAGGCTTCCGTCGGCGCGCCCGCACCAAAAGGCCCCGCCAAACCGGTGCTGCCTGCGGTTAAAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comE | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comE | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comE | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |