Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   NC855_RS11010 Genome accession   NZ_CP098472
Coordinates   2100193..2101446 (+) Length   417 a.a.
NCBI ID   WP_003687004.1    Uniprot ID   A0AB74EGQ8
Organism   Neisseria gonorrhoeae strain 10612     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2095193..2106446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NC855_RS10990 (NC855_10910) - 2095944..2096945 (+) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -
  NC855_RS10995 (NC855_10915) - 2097039..2097887 (+) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  NC855_RS11000 (NC855_10920) - 2097913..2098395 (+) 483 WP_003694396.1 CinA family protein -
  NC855_RS11005 (NC855_10925) msrAB 2098479..2100047 (-) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  NC855_RS11010 (NC855_10930) pilA 2100193..2101446 (+) 1254 WP_003687004.1 signal recognition particle-docking protein FtsY Machinery gene
  NC855_RS11015 (NC855_10935) - 2101524..2101697 (-) 174 WP_167550559.1 hypothetical protein -
  NC855_RS11020 (NC855_10940) - 2101711..2102571 (-) 861 WP_267747190.1 opacity family porin -
  NC855_RS12035 pilE 2103002..2103166 (-) 165 WP_003699316.1 hypothetical protein Machinery gene
  NC855_RS11030 (NC855_10950) pilE 2103139..2103507 (-) 369 WP_267747191.1 pilin Machinery gene
  NC855_RS11035 (NC855_10955) - 2103876..2104019 (-) 144 WP_012503975.1 hypothetical protein -
  NC855_RS11045 (NC855_10965) - 2104322..2104665 (-) 344 Protein_2132 pilin -
  NC855_RS12040 - 2104719..2104871 (-) 153 Protein_2133 pilin -
  NC855_RS11055 (NC855_10975) - 2105005..2105398 (-) 394 Protein_2134 pilin -
  NC855_RS11060 (NC855_10980) - 2105935..2106278 (-) 344 Protein_2135 pilin -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44389.74 Da        Isoelectric Point: 4.8123

>NTDB_id=696002 NC855_RS11010 WP_003687004.1 2100193..2101446(+) (pilA) [Neisseria gonorrhoeae strain 10612]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=696002 NC855_RS11010 WP_003687004.1 2100193..2101446(+) (pilA) [Neisseria gonorrhoeae strain 10612]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGTTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTCATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCGGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGTCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.76

100

0.998