Detailed information NTG0695392

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: NCL52_RS12820
• Genome accession: NZ_CP098417
• Coordinates: 2502406..2504736 (-)
• Length: 776 a.a.
• NCBI ID: WP_137200851.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain N2-10
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2497406..2509736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NCL52_RS12785 (NCL52_12785)	yqxA	2497745..2498083 (-)	339	WP_086344100.1	YqxA family protein	-
NCL52_RS12790 (NCL52_12790)	spoIIP	2498100..2499305 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
NCL52_RS12795 (NCL52_12795)	gpr	2499368..2500474 (-)	1107	WP_014480309.1	GPR endopeptidase	-
NCL52_RS12800 (NCL52_12800)	rpsT	2500678..2500944 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
NCL52_RS12805 (NCL52_12805)	holA	2500959..2502002 (-)	1044	WP_015714286.1	DNA polymerase III subunit delta	-
NCL52_RS12810 (NCL52_12810)	-	2502042..2502191 (-)	150	WP_120363468.1	hypothetical protein	-
NCL52_RS12815 (NCL52_12815)	yqzM	2502232..2502366 (+)	135	WP_003229983.1	YqzM family protein	-
NCL52_RS12820 (NCL52_12820)	comEC	2502406..2504736 (-)	2331	WP_137200851.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NCL52_RS12825 (NCL52_12825)	comEB	2504740..2505309 (-)	570	WP_003229978.1	ComE operon protein 2	-
NCL52_RS12830 (NCL52_12830)	comEA	2505376..2505993 (-)	618	WP_137200853.1	competence protein ComEA	Machinery gene
NCL52_RS12835 (NCL52_12835)	comER	2506077..2506898 (+)	822	WP_134981848.1	late competence protein ComER	-
NCL52_RS12840 (NCL52_12840)	yqeM	2506964..2507707 (-)	744	WP_033884459.1	class I SAM-dependent methyltransferase	-
NCL52_RS12845 (NCL52_12845)	rsfS	2507704..2508060 (-)	357	WP_014480315.1	ribosome silencing factor	-
NCL52_RS12850 (NCL52_12850)	yqeK	2508078..2508638 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
NCL52_RS12855 (NCL52_12855)	nadD	2508628..2509197 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
NCL52_RS12860 (NCL52_12860)	yhbY	2509209..2509499 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86814.45 Da
• Isoelectric Point: 7.0495

>NTDB_id=695392 NCL52_RS12820 WP_137200851.1 2502406..2504736(-) (comEC) [Bacillus subtilis strain N2-10]
MRNSRLLLPMAAASATVGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVKTPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYKEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIIIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMAGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIIHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKMLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVERGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHFIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=695392 NCL52_RS12820 WP_137200851.1 2502406..2504736(-) (comEC) [Bacillus subtilis strain N2-10]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGTTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAAAGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGTGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGAATTGTACAGGCACTTACAGTCGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCGATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATAATCCGTCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGGCGGGTGTTTACTTAG
CTGGAAGTCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGTTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCATACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGCGGC
ATTTGCTGCACGGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGTATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGATGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGGAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
GCACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGAAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTTTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.68	100	0.977