Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   NB629_RS12990 Genome accession   NZ_CP098253
Coordinates   2661593..2662279 (+) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain M0     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2656593..2667279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NB629_RS12955 (NB629_12955) yqeH 2657120..2658220 (+) 1101 WP_001280132.1 ribosome biogenesis GTPase YqeH -
  NB629_RS12960 (NB629_12960) aroE 2658234..2659040 (+) 807 WP_000666750.1 shikimate dehydrogenase -
  NB629_RS12965 (NB629_12965) yhbY 2659044..2659334 (+) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  NB629_RS12970 (NB629_12970) nadD 2659337..2659906 (+) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  NB629_RS12975 (NB629_12975) yqeK 2659896..2660480 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  NB629_RS12980 (NB629_12980) rsfS 2660481..2660834 (+) 354 WP_001088020.1 ribosome silencing factor -
  NB629_RS12985 (NB629_12985) - 2660837..2661553 (+) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  NB629_RS12990 (NB629_12990) comEA 2661593..2662279 (+) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  NB629_RS12995 (NB629_12995) - 2662371..2662832 (+) 462 WP_000439692.1 ComE operon protein 2 -
  NB629_RS13000 (NB629_13000) comEC 2662837..2665038 (+) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NB629_RS13005 (NB629_13005) holA 2665095..2666069 (+) 975 WP_001282570.1 DNA polymerase III subunit delta -
  NB629_RS13010 (NB629_13010) rpsT 2666114..2666365 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=694775 NB629_RS12990 WP_001794049.1 2661593..2662279(+) (comEA) [Staphylococcus aureus strain M0]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=694775 NB629_RS12990 WP_001794049.1 2661593..2662279(+) (comEA) [Staphylococcus aureus strain M0]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952