Detailed information NTG0069331

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: MDRSPN_RS08570
• Genome accession: NZ_AP018391
• Coordinates: 1643393..1644460 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159562.1
• Uniprot ID: B1I897
• Organism: Streptococcus pneumoniae strain MDRSPN001
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1638393..1649460

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MDRSPN_RS08545 (MDRSPN_01629)	treR	1638784..1639494 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
MDRSPN_RS08555	-	1639649..1640904 (+)	1256	WP_408990149.1	ISL3 family transposase	-
MDRSPN_RS08560 (MDRSPN_01632)	-	1641019..1642275 (+)	1257	WP_000436628.1	ISL3 family transposase	-
MDRSPN_RS08565 (MDRSPN_01633)	amiF	1642456..1643382 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
MDRSPN_RS08570 (MDRSPN_01634)	amiE	1643393..1644460 (-)	1068	WP_000159562.1	ABC transporter ATP-binding protein	Regulator
MDRSPN_RS08575 (MDRSPN_01635)	amiD	1644469..1645395 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
MDRSPN_RS08580 (MDRSPN_01636)	amiC	1645395..1646891 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
MDRSPN_RS08585 (MDRSPN_01637)	amiA3	1646958..1648937 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=69331 MDRSPN_RS08570 WP_000159562.1 1643393..1644460(-) (amiE) [Streptococcus pneumoniae strain MDRSPN001]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKEWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=69331 MDRSPN_RS08570 WP_000159562.1 1643393..1644460(-) (amiE) [Streptococcus pneumoniae strain MDRSPN001]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGAGTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: B1I897

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538