Detailed information NTG0069329

Bioinformatically predicted

Overview

• Name: treR
• Type: Regulator
• Locus tag: MDRSPN_RS08545
• Genome accession: NZ_AP018391
• Coordinates: 1638784..1639494 (+)
• Length: 236 a.a.
• NCBI ID: WP_000760673.1
• Uniprot ID: A0A062WVH4
• Organism: Streptococcus pneumoniae strain MDRSPN001
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1639649..1642275	1638784..1639494	flank	155

Gene organization within MGE regions

Location: 1638784..1642275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MDRSPN_RS08545 (MDRSPN_01629)	treR	1638784..1639494 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
MDRSPN_RS08555	-	1639649..1640904 (+)	1256	WP_408990149.1	ISL3 family transposase	-
MDRSPN_RS08560 (MDRSPN_01632)	-	1641019..1642275 (+)	1257	WP_000436628.1	ISL3 family transposase	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27607.78 Da
• Isoelectric Point: 8.9698

>NTDB_id=69329 MDRSPN_RS08545 WP_000760673.1 1638784..1639494(+) (treR) [Streptococcus pneumoniae strain MDRSPN001]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide

• Length: 711 bp

>NTDB_id=69329 MDRSPN_RS08545 WP_000760673.1 1638784..1639494(+) (treR) [Streptococcus pneumoniae strain MDRSPN001]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACAGACTATCTGGATATGGAACTCATCCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAGAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, gntR family (GntR) (3-66)

• UTRA domain (UTRA) (89-227)

3D structure

• AlphaFold DB: A0A062WVH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
treR	Streptococcus mutans UA159	59.322	100	0.593