Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   O3296_RS09365 Genome accession   NZ_CP114592
Coordinates   1937815..1938471 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain WEC     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1932815..1943471
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O3296_RS09335 (O3296_09335) dcyD 1933694..1934680 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  O3296_RS09340 (O3296_09340) tcyL 1934695..1935363 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  O3296_RS09345 (O3296_09345) tcyN 1935360..1936112 (+) 753 WP_227455471.1 L-cystine ABC transporter ATP-binding protein TcyN -
  O3296_RS09350 (O3296_09350) sdiA 1936342..1937064 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  O3296_RS09355 (O3296_09355) yecF 1937132..1937356 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  O3296_RS09360 (O3296_09360) yecU 1937343..1937519 (-) 177 WP_000590347.1 protein YecU -
  O3296_RS09365 (O3296_09365) letA 1937815..1938471 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  O3296_RS09370 (O3296_09370) uvrC 1938468..1940300 (+) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  O3296_RS09375 (O3296_09375) pgsA 1940357..1940905 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  O3296_RS09395 (O3296_09395) yecA 1941555..1942220 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=693255 O3296_RS09365 WP_000611328.1 1937815..1938471(+) (letA) [Escherichia coli strain WEC]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=693255 O3296_RS09365 WP_000611328.1 1937815..1938471(+) (letA) [Escherichia coli strain WEC]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
AATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482