Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   MDRSPN_RS06800 Genome accession   NZ_AP018391
Coordinates   1313913..1315145 (-) Length   410 a.a.
NCBI ID   WP_000106347.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain MDRSPN001     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1308913..1320145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MDRSPN_RS06770 (MDRSPN_01285) - 1309100..1310068 (+) 969 WP_000081004.1 NAD(P)/FAD-dependent oxidoreductase -
  MDRSPN_RS06775 (MDRSPN_01286) whiA 1310102..1311013 (-) 912 WP_004262315.1 DNA-binding protein WhiA -
  MDRSPN_RS06780 (MDRSPN_01287) - 1311010..1311987 (-) 978 WP_120164250.1 YvcK family protein -
  MDRSPN_RS06785 (MDRSPN_01288) rapZ 1311984..1312874 (-) 891 WP_049499710.1 RNase adapter RapZ -
  MDRSPN_RS06790 (MDRSPN_01289) - 1312926..1313306 (-) 381 WP_001140412.1 RidA family protein -
  MDRSPN_RS06795 (MDRSPN_01290) yihA 1313317..1313904 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  MDRSPN_RS06800 (MDRSPN_01291) clpX 1313913..1315145 (-) 1233 WP_000106347.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  MDRSPN_RS06810 (MDRSPN_01293) - 1315347..1315853 (-) 507 WP_000162494.1 dihydrofolate reductase -
  MDRSPN_RS06815 (MDRSPN_01294) - 1315983..1316501 (-) 519 WP_000229874.1 DNA starvation/stationary phase protection protein -
  MDRSPN_RS06820 (MDRSPN_01295) lytC 1316998..1318503 (-) 1506 WP_013193470.1 choline binding-anchored murein hydrolase LytC -
  MDRSPN_RS06825 (MDRSPN_01296) tpiA 1318541..1319299 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  MDRSPN_RS06830 (MDRSPN_01297) - 1319398..1320075 (-) 678 WP_000221584.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45797.41 Da        Isoelectric Point: 4.5109

>NTDB_id=69324 MDRSPN_RS06800 WP_000106347.1 1313913..1315145(-) (clpX) [Streptococcus pneumoniae strain MDRSPN001]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELKFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=69324 MDRSPN_RS06800 WP_000106347.1 1313913..1315145(-) (clpX) [Streptococcus pneumoniae strain MDRSPN001]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTTCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGAAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment