Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MDRSPN_RS01820 Genome accession   NZ_AP018391
Coordinates   340151..340840 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain MDRSPN001     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 335151..345840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MDRSPN_RS01795 (MDRSPN_00338) gpsB 335248..335589 (+) 342 WP_061762438.1 cell division regulator GpsB -
  MDRSPN_RS01805 (MDRSPN_00339) - 336075..337232 (+) 1158 WP_000711398.1 class I SAM-dependent RNA methyltransferase -
  MDRSPN_RS01810 (MDRSPN_00340) mapZ 337245..338639 (+) 1395 WP_000039290.1 mid-cell-anchored protein MapZ -
  MDRSPN_RS01815 (MDRSPN_00341) gndA 338715..340139 (+) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  MDRSPN_RS01820 (MDRSPN_00342) covR 340151..340840 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  MDRSPN_RS01825 (MDRSPN_00343) cbpC 340938..341900 (+) 963 WP_000698035.1 choline-binding protein CbpC -
  MDRSPN_RS01830 (MDRSPN_00344) cbpJ 341919..342917 (+) 999 WP_000771128.1 choline-binding protein CbpJ -
  MDRSPN_RS01835 (MDRSPN_00345) - 343035..344267 (-) 1233 WP_000765677.1 MFS transporter -
  MDRSPN_RS01840 (MDRSPN_00346) - 344310..344897 (-) 588 WP_001822134.1 lanthionine synthetase LanC family protein -
  MDRSPN_RS11155 - 344797..345186 (-) 390 WP_001865604.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=69300 MDRSPN_RS01820 WP_000518011.1 340151..340840(+) (covR) [Streptococcus pneumoniae strain MDRSPN001]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=69300 MDRSPN_RS01820 WP_000518011.1 340151..340840(+) (covR) [Streptococcus pneumoniae strain MDRSPN001]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment