Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   M9H69_RS08210 Genome accession   NZ_CP097843
Coordinates   1604770..1605459 (-) Length   229 a.a.
NCBI ID   WP_250315354.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1599770..1610459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS08190 (M9H69_08190) - 1600724..1601731 (-) 1008 WP_250315350.1 phosphomevalonate kinase -
  M9H69_RS08195 (M9H69_08195) mvaD 1601718..1602671 (-) 954 WP_250315351.1 diphosphomevalonate decarboxylase -
  M9H69_RS08200 (M9H69_08200) mvk 1602653..1603531 (-) 879 WP_250315352.1 mevalonate kinase -
  M9H69_RS08205 (M9H69_08205) cbpC 1603651..1604670 (-) 1020 WP_250315353.1 choline-binding protein CbpC -
  M9H69_RS08210 (M9H69_08210) covR 1604770..1605459 (-) 690 WP_250315354.1 response regulator transcription factor Regulator
  M9H69_RS08215 (M9H69_08215) gndA 1605471..1606895 (-) 1425 WP_007518502.1 NADP-dependent phosphogluconate dehydrogenase -
  M9H69_RS08220 (M9H69_08220) - 1606971..1608413 (-) 1443 WP_250315355.1 cell division site-positioning protein MapZ family protein -
  M9H69_RS08225 (M9H69_08225) - 1608426..1609583 (-) 1158 WP_250315356.1 class I SAM-dependent RNA methyltransferase -
  M9H69_RS08235 (M9H69_08235) gpsB 1610077..1610406 (-) 330 WP_125391499.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26851.05 Da        Isoelectric Point: 9.3098

>NTDB_id=692943 M9H69_RS08210 WP_250315354.1 1604770..1605459(-) (covR) [Streptococcus oralis strain HP01]
MGKRILLHEKERNLARFLSLELQKEQYRVDLVEKGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIIVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=692943 M9H69_RS08210 WP_250315354.1 1604770..1605459(-) (covR) [Streptococcus oralis strain HP01]
ATGGGGAAACGGATTTTATTACATGAGAAAGAACGAAATCTCGCTCGTTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTTGTAGAGAAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACAGCCCAGGATTTTGCAGAGAGGCTTAGTCGGACAAAACCAGCCTCAGTGATTATAGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGATTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATTGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCATACCGTAACCTACGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAGACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

47.368

99.563

0.472