Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   M9H69_RS01640 Genome accession   NZ_CP097843
Coordinates   292700..293524 (+) Length   274 a.a.
NCBI ID   WP_250315736.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 287700..298524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS01605 (M9H69_01605) asnA 287790..288782 (+) 993 WP_000747987.1 aspartate--ammonia ligase -
  M9H69_RS01610 (M9H69_01610) rsmD 288847..289386 (+) 540 WP_250315733.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  M9H69_RS01615 (M9H69_01615) coaD 289376..289864 (+) 489 WP_250315734.1 pantetheine-phosphate adenylyltransferase -
  M9H69_RS01620 (M9H69_01620) sepM 289848..290885 (+) 1038 WP_250315735.1 SepM family pheromone-processing serine protease Regulator
  M9H69_RS01625 (M9H69_01625) - 290941..291171 (+) 231 WP_084911818.1 DUF1146 family protein -
  M9H69_RS01630 (M9H69_01630) murA 291195..292478 (+) 1284 WP_084874506.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  M9H69_RS01635 (M9H69_01635) - 292465..292659 (+) 195 WP_061415718.1 DNA-directed RNA polymerase subunit beta -
  M9H69_RS01640 (M9H69_01640) endA 292700..293524 (+) 825 WP_250315736.1 DNA/RNA non-specific endonuclease Machinery gene
  M9H69_RS01645 (M9H69_01645) - 293660..294991 (+) 1332 WP_250315737.1 hemolysin family protein -
  M9H69_RS01655 (M9H69_01655) amiA3 295499..297475 (+) 1977 WP_250315738.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29995.58 Da        Isoelectric Point: 9.8128

>NTDB_id=692909 M9H69_RS01640 WP_250315736.1 292700..293524(+) (endA) [Streptococcus oralis strain HP01]
MDKKTRQTLIGLLLFLLLAAGSYYIKQMQSASNSPRTKVSQKKQASEAPSQELAESVLTESIKNQIKGDLEWNGAGAFVV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKSLDKNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=692909 M9H69_RS01640 WP_250315736.1 292700..293524(+) (endA) [Streptococcus oralis strain HP01]
ATGGACAAAAAAACAAGACAGACTTTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCGGGAAGCTATTATATCAAGCA
GATGCAATCGGCATCAAATAGCCCTCGAACTAAGGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCCAGTCAGGAGCTGG
CTGAAAGTGTCTTAACTGAGTCGATAAAGAACCAAATCAAGGGGGATCTCGAGTGGAATGGAGCAGGGGCTTTTGTTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCAAGCAAACCCTATGCGGATAATAAAACAAAGACAGTTGGAAAAGA
AACAGTCCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAAACAGGAAATGGAT
CCACCTCTTGGACGCCACCAGGATGGCATCAGGTTAAGAATCTAAAGGGAGCCTACACACATGCAGTCGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCTAAGAATATTGCAGTCCAGAC
AGCCTGGGCTAACCAAGCGCAGGCTGAAGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAATCCTTGGACA
AAAATAAGAGGGTCCGTTACCGCGTGACACTCCACTATGCGACAAATGAGGATCTAGTTCCATCTGCTTCACAAATTGAA
GCCAAATCTTCGGATGGCGAATTGGAGTTCAACGTGCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGGCAAGTAACAGTGACAGATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.011

99.635

0.887
  endA Streptococcus pneumoniae D39

89.011

99.635

0.887
  endA Streptococcus pneumoniae R6

89.011

99.635

0.887
  endA Streptococcus pneumoniae TIGR4

89.011

99.635

0.887