Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   EP180_RS06870 Genome accession   NZ_AP018385
Coordinates   1151963..1152358 (-) Length   131 a.a.
NCBI ID   WP_003703428.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain FC498     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1147901..1159155 1151963..1152358 within 0


Gene organization within MGE regions


Location: 1147901..1159155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP180_RS14635 (NgFC498_01197) - 1147901..1148497 (-) 597 WP_012503916.1 TIGR02391 family protein -
  EP180_RS14640 (NgFC498_01198) - 1148687..1149544 (-) 858 WP_012503917.1 ATP-binding protein -
  EP180_RS06845 (NgFC498_01199) - 1149558..1149992 (-) 435 WP_229684538.1 DNA cytosine methyltransferase -
  EP180_RS06850 - 1149926..1150534 (-) 609 WP_080229275.1 DNA cytosine methyltransferase -
  EP180_RS06865 (NgFC498_01202) comP 1151426..1151875 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene
  EP180_RS06870 (NgFC498_01203) comE 1151963..1152358 (-) 396 WP_003703428.1 helix-hairpin-helix domain-containing protein Machinery gene
  EP180_RS14645 - 1152463..1152579 (-) 117 Protein_1192 competence protein ComE -
  EP180_RS06910 (NgFC498_01209) - 1158204..1158857 (-) 654 Protein_1193 TIGR01621 family pseudouridine synthase -
  EP180_RS06915 (NgFC498_01210) - 1158811..1159134 (-) 324 WP_003689613.1 HAD hydrolase family protein -

Sequence

Protein


Download         Length: 131 a.a.        Molecular weight: 13796.61 Da        Isoelectric Point: 10.8790

>NTDB_id=69272 EP180_RS06870 WP_003703428.1 1151963..1152358(-) (comE) [Neisseria gonorrhoeae strain FC498]
MSRGGATPYRFLLIRHIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINAASQQELEALPGIGPAKAKAIAEY
RAQNGAFKSVDDLIKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPAVKK

Nucleotide


Download         Length: 396 bp        

>NTDB_id=69272 EP180_RS06870 WP_003703428.1 1151963..1152358(-) (comE) [Neisseria gonorrhoeae strain FC498]
TTGAGCCGGGGCGGGGCAACGCCGTACCGGTTTTTGTTAATCCGCCATATCGTCGCAAGATGCGGTTTGTTGTTTGCAAC
CCTTAAAGGAAAAACCATGAAAAAAATGTTTGTATTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAA
ACATCAATGCGGCTTCGCAGCAGGAGCTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATAC
CGCGCGCAAAACGGCGCGTTCAAGTCTGTGGACGATTTGATCAAGGTGAAGGGCATCGGTCCGGCGGTGCTGGCGAAGCT
GAAAGACCAGGCTTCCGTCGGCGCGCCCGCACCAAAAGGCCCCGCCAAACCGGTGCTGCCTGCGGTTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(52-110)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1
  comE Neisseria gonorrhoeae MS11

100

100

1

Multiple sequence alignment