Detailed information
Bioinformatically predicted
Overview
| Name | recD | Type | Machinery gene |
| Locus tag | EP179_RS04475 | Genome accession | NZ_AP018381 |
| Coordinates | 766155..767900 (+) | Length | 581 a.a. |
| NCBI ID | WP_003688652.1 | Uniprot ID | A0AA44U7G6 |
| Organism | Neisseria gonorrhoeae strain FC460 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 730982..806029 | 766155..767900 | within | 0 |
| IS/Tn | 768587..769588 | 766155..767900 | flank | 687 |
Gene organization within MGE regions
Location: 730982..806029
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EP179_RS04255 (NgFC460_00744) | - | 730982..732052 (-) | 1071 | WP_010360162.1 | tyrosine-type recombinase/integrase | - |
| EP179_RS04260 (NgFC460_00745) | - | 732261..733040 (-) | 780 | WP_003688701.1 | ferredoxin--NADP reductase | - |
| EP179_RS04275 | - | 733632..733841 (-) | 210 | WP_003688699.1 | hypothetical protein | - |
| EP179_RS04280 (NgFC460_00747) | dinB | 733940..734998 (+) | 1059 | WP_003695315.1 | DNA polymerase IV | - |
| EP179_RS04285 (NgFC460_00748) | rep | 735068..737083 (-) | 2016 | WP_012503651.1 | DNA helicase Rep | - |
| EP179_RS04290 (NgFC460_00749) | aroD | 737103..737867 (-) | 765 | WP_003688696.1 | type I 3-dehydroquinate dehydratase | - |
| EP179_RS04295 (NgFC460_00750) | recA | 738067..739113 (+) | 1047 | WP_003688695.1 | recombinase RecA | Machinery gene |
| EP179_RS04310 (NgFC460_00751) | - | 739766..740101 (-) | 336 | WP_003688693.1 | YbaB/EbfC family nucleoid-associated protein | - |
| EP179_RS04315 (NgFC460_00752) | dnaX | 740182..742305 (-) | 2124 | WP_003695312.1 | DNA polymerase III subunit gamma/tau | - |
| EP179_RS04320 (NgFC460_00753) | mutL | 742400..744364 (-) | 1965 | WP_047926984.1 | DNA mismatch repair endonuclease MutL | - |
| EP179_RS04325 (NgFC460_00754) | - | 744508..744693 (+) | 186 | WP_003688687.1 | DUF3460 family protein | - |
| EP179_RS04330 (NgFC460_00755) | - | 744704..745372 (+) | 669 | WP_003688686.1 | class I SAM-dependent methyltransferase | - |
| EP179_RS04335 (NgFC460_00756) | - | 745372..746085 (+) | 714 | WP_003697104.1 | tetratricopeptide repeat protein | - |
| EP179_RS04340 (NgFC460_00757) | purE | 746133..746618 (+) | 486 | WP_003688684.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| EP179_RS04350 (NgFC460_00758) | - | 746830..747637 (-) | 808 | Protein_753 | transposase | - |
| EP179_RS04360 | - | 748011..748376 (+) | 366 | Protein_754 | transposase | - |
| EP179_RS04365 (NgFC460_00760) | - | 748383..749408 (+) | 1026 | Protein_755 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| EP179_RS04370 (NgFC460_00761) | - | 749603..750259 (-) | 657 | WP_003688682.1 | response regulator | - |
| EP179_RS04375 (NgFC460_00762) | - | 750256..752025 (-) | 1770 | WP_003688681.1 | histidine kinase | - |
| EP179_RS04380 (NgFC460_00763) | - | 752232..752846 (+) | 615 | WP_047917856.1 | molybdenum cofactor guanylyltransferase | - |
| EP179_RS04385 (NgFC460_00764) | - | 753009..753626 (+) | 618 | WP_010358100.1 | riboflavin synthase | - |
| EP179_RS04390 | - | 753634..754498 (+) | 865 | Protein_760 | ATP-binding protein | - |
| EP179_RS04395 (NgFC460_00767) | - | 754511..754945 (-) | 435 | WP_003688677.1 | Spy/CpxP family protein refolding chaperone | - |
| EP179_RS04400 (NgFC460_00768) | rpe | 755091..755774 (+) | 684 | WP_003688675.1 | ribulose-phosphate 3-epimerase | - |
| EP179_RS04410 (NgFC460_00769) | ruvB | 756019..757050 (-) | 1032 | WP_003688673.1 | Holliday junction branch migration DNA helicase RuvB | - |
| EP179_RS04415 (NgFC460_00770) | - | 757132..757440 (-) | 309 | WP_003688671.1 | hypothetical protein | - |
| EP179_RS04425 (NgFC460_00771) | - | 757859..759091 (-) | 1233 | WP_003702731.1 | multifunctional CCA addition/repair protein | - |
| EP179_RS04430 (NgFC460_00772) | - | 759170..760798 (-) | 1629 | WP_010951119.1 | ABC-F family ATPase | - |
| EP179_RS04435 (NgFC460_00773) | - | 760948..761322 (+) | 375 | WP_003688664.1 | arsenate reductase | - |
| EP179_RS04440 (NgFC460_00774) | - | 761371..762909 (+) | 1539 | WP_003695299.1 | SurA N-terminal domain-containing protein | - |
| EP179_RS04445 (NgFC460_00775) | recR | 762976..763593 (+) | 618 | WP_003688660.1 | recombination mediator RecR | - |
| EP179_RS04450 (NgFC460_00776) | - | 763649..763927 (-) | 279 | WP_003688659.1 | hypothetical protein | - |
| EP179_RS04465 (NgFC460_00777) | - | 764153..765400 (+) | 1248 | WP_003691197.1 | lipoprotein-releasing ABC transporter permease subunit | - |
| EP179_RS04470 (NgFC460_00778) | lolD | 765393..766088 (+) | 696 | WP_003688655.1 | lipoprotein-releasing ABC transporter ATP-binding protein LolD | - |
| EP179_RS04475 (NgFC460_00779) | recD | 766155..767900 (+) | 1746 | WP_003688652.1 | exodeoxyribonuclease V subunit alpha | Machinery gene |
| EP179_RS04480 | - | 767972..768618 (-) | 647 | Protein_774 | methyltransferase | - |
| EP179_RS04485 (NgFC460_00781) | - | 768626..769588 (+) | 963 | WP_127466217.1 | IS110 family transposase | - |
| EP179_RS13565 | - | 769717..770176 (-) | 460 | Protein_776 | methyltransferase | - |
| EP179_RS04495 (NgFC460_00783) | lon | 770428..772890 (+) | 2463 | WP_003688644.1 | endopeptidase La | - |
| EP179_RS04500 (NgFC460_00784) | - | 773072..773341 (+) | 270 | WP_003688640.1 | HU family DNA-binding protein | - |
| EP179_RS04505 (NgFC460_00785) | - | 773517..773951 (-) | 435 | WP_003688638.1 | hypothetical protein | - |
| EP179_RS04510 (NgFC460_00786) | - | 773944..775251 (-) | 1308 | WP_103195193.1 | homoserine dehydrogenase | - |
| EP179_RS04515 (NgFC460_00787) | - | 775447..775818 (+) | 372 | WP_003688636.1 | Mth938-like domain-containing protein | - |
| EP179_RS04520 (NgFC460_00788) | - | 775895..777817 (+) | 1923 | WP_003691184.1 | ATP-binding cassette domain-containing protein | - |
| EP179_RS04525 | - | 777780..778199 (+) | 420 | WP_229692939.1 | DUF4124 domain-containing protein | - |
| EP179_RS04530 (NgFC460_00789) | - | 778290..778802 (+) | 513 | WP_003693093.1 | hypothetical protein | - |
| EP179_RS04535 (NgFC460_00790) | - | 779232..779927 (-) | 696 | WP_033910499.1 | DUF4400 domain-containing protein | - |
| EP179_RS04540 (NgFC460_00791) | traD | 779917..781959 (-) | 2043 | WP_012503640.1 | type IV conjugative transfer system coupling protein TraD | - |
| EP179_RS04545 (NgFC460_00792) | mobH | 781956..784508 (-) | 2553 | WP_012503639.1 | MobH family relaxase | - |
| EP179_RS04550 (NgFC460_00793) | - | 784505..784924 (-) | 420 | WP_003693104.1 | hypothetical protein | - |
| EP179_RS04555 (NgFC460_00794) | - | 785435..785896 (+) | 462 | WP_012503638.1 | lytic transglycosylase domain-containing protein | - |
| EP179_RS04560 (NgFC460_00795) | - | 785866..786387 (+) | 522 | WP_003695285.1 | OmpA family protein | - |
| EP179_RS04565 (NgFC460_00796) | traA | 786443..786739 (+) | 297 | WP_003697092.1 | TraA family conjugative transfer protein | - |
| EP179_RS04570 (NgFC460_00797) | traL | 786761..787042 (+) | 282 | WP_003693110.1 | type IV conjugative transfer system protein TraL | - |
| EP179_RS04575 (NgFC460_00798) | - | 787039..787704 (+) | 666 | WP_003704028.1 | conjugal transfer protein TraE | - |
| EP179_RS04580 (NgFC460_00799) | - | 787706..788440 (+) | 735 | WP_003693114.1 | TraK domain-containing protein | - |
| EP179_RS04585 (NgFC460_00800) | - | 788442..789755 (+) | 1314 | WP_003697090.1 | TrbI/VirB10 family protein | - |
| EP179_RS04590 (NgFC460_00801) | - | 789765..790484 (+) | 720 | WP_003693119.1 | DsbC family protein | - |
| EP179_RS04595 (NgFC460_00802) | - | 790481..791062 (+) | 582 | WP_017146802.1 | TraV family lipoprotein | - |
| EP179_RS04600 (NgFC460_00803) | traC | 791072..793648 (+) | 2577 | WP_003693122.1 | type IV secretion system protein TraC | - |
| EP179_RS04605 (NgFC460_00804) | - | 793676..794224 (+) | 549 | WP_003695274.1 | hypothetical protein | - |
| EP179_RS04610 (NgFC460_00805) | - | 794224..794769 (+) | 546 | WP_003704029.1 | S26 family signal peptidase | - |
| EP179_RS04615 (NgFC460_00806) | - | 794778..795434 (+) | 657 | WP_003693128.1 | hypothetical protein | - |
| EP179_RS04620 (NgFC460_00807) | - | 795431..796549 (+) | 1119 | WP_003695266.1 | TraU family protein | - |
| EP179_RS14595 | - | 796576..796749 (-) | 174 | WP_228369789.1 | hypothetical protein | - |
| EP179_RS14600 | trbC | 796834..797316 (+) | 483 | WP_228369788.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EP179_RS04630 (NgFC460_00809) | - | 797313..798557 (+) | 1245 | WP_003695263.1 | hypothetical protein | - |
| EP179_RS04635 (NgFC460_00810) | traN | 798596..800137 (+) | 1542 | WP_226876101.1 | conjugal transfer protein TraN | - |
| EP179_RS04640 (NgFC460_00811) | - | 800124..800549 (+) | 426 | WP_003693140.1 | hypothetical protein | - |
| EP179_RS04645 (NgFC460_00812) | - | 800561..801337 (+) | 777 | WP_012503632.1 | thioredoxin family protein | - |
| EP179_RS04650 (NgFC460_00813) | - | 801509..803020 (+) | 1512 | WP_041421275.1 | conjugal transfer protein TraH | - |
| EP179_RS04655 (NgFC460_00814) | - | 803027..806029 (+) | 3003 | WP_012503630.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
Sequence
Protein
Download Length: 581 a.a. Molecular weight: 63039.83 Da Isoelectric Point: 6.0083
>NTDB_id=69223 EP179_RS04475 WP_003688652.1 766155..767900(+) (recD) [Neisseria gonorrhoeae strain FC460]
MELQTDEFAQAAARAAIRFLERYAGSGNEVLANCTERLFQALQNGHSFIRLSGDEADALSALAPVVGTSAAPLILEGRRL
FLGRMWQLEYDLAAEIKRLAAAGTSAPDAAGARQNLAKWFQGAGSEGQRDAAALALLQFFMVITGGPGTGKTTTVAKLLA
LICGENENLPHIALAAPTGKAAAHMARALHRAINGFDAPEAVRRHLLKLEGQTVHRLLKLSPPKMQAAFDHIRPLPFDVL
IVDEASMLDTALMLQLLKAVKTGARVILLGDENQLPSVGIGAVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPVLA
QNTAHLSFSHRFGDNSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGNIEAAYAGI
SDIVVLAAWRQDAEDFNEAYCSYVRRKMNIPEHLAYFAGEPIMIRQNDYALELFNGDIGLIMEDVGRQGSLAAYFADADG
FKKVAVSCLPEFEPAFAMTVHKSQGSEYREVWLLPPSDAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGKKTFCQAV
NTVKVRQTALGSMLERVFSQE
MELQTDEFAQAAARAAIRFLERYAGSGNEVLANCTERLFQALQNGHSFIRLSGDEADALSALAPVVGTSAAPLILEGRRL
FLGRMWQLEYDLAAEIKRLAAAGTSAPDAAGARQNLAKWFQGAGSEGQRDAAALALLQFFMVITGGPGTGKTTTVAKLLA
LICGENENLPHIALAAPTGKAAAHMARALHRAINGFDAPEAVRRHLLKLEGQTVHRLLKLSPPKMQAAFDHIRPLPFDVL
IVDEASMLDTALMLQLLKAVKTGARVILLGDENQLPSVGIGAVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPVLA
QNTAHLSFSHRFGDNSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGNIEAAYAGI
SDIVVLAAWRQDAEDFNEAYCSYVRRKMNIPEHLAYFAGEPIMIRQNDYALELFNGDIGLIMEDVGRQGSLAAYFADADG
FKKVAVSCLPEFEPAFAMTVHKSQGSEYREVWLLPPSDAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGKKTFCQAV
NTVKVRQTALGSMLERVFSQE
Nucleotide
Download Length: 1746 bp
>NTDB_id=69223 EP179_RS04475 WP_003688652.1 766155..767900(+) (recD) [Neisseria gonorrhoeae strain FC460]
ATGGAACTGCAGACAGATGAATTTGCCCAAGCGGCGGCAAGGGCGGCAATCCGTTTTTTGGAACGCTATGCGGGTTCGGG
CAACGAAGTGCTTGCAAACTGTACCGAACGCCTGTTTCAGGCATTGCAAAACGGTCATTCGTTTATCCGTTTGAGCGGGG
ACGAGGCTGACGCGCTGTCGGCACTCGCACCCGTGGTCGGAACATCCGCCGCGCCTTTGATTTTGGAAGGCAGAAGGCTG
TTTTTGGGCAGGATGTGGCAGTTGGAATACGATTTGGCTGCCGAAATAAAACGCTTGGCGGCAGCCGGCACGTCCGCCCC
CGACGCGGCAGGCGCGCGGCAAAACCTCGCAAAATGGTTTCAAGGCGCGGGAAGCGAAGGACAGCGCGATGCGGCCGCCT
TGGCACTGTTGCAGTTTTTTATGGTGATTACCGGAGGGCCGGGAACGGGCAAAACGACAACGGTTGCCAAACTGCTGGCA
CTGATTTGCGGTGAAAACGAAAATCTTCCCCATATCGCGCTTGCCGCACCGACGGGCAAAGCGGCGGCACATATGGCGCG
CGCGCTGCACCGTGCAATCAACGGTTTTGACGCGCCGGAGGCCGTCCGCCGCCATTTGCTCAAACTGGAAGGGCAAACCG
TCCACCGACTGCTTAAGCTGAGCCCGCCCAAAATGCAGGCGGCGTTCGACCATATCCGTCCGCTGCCGTTCGACGTGCTG
ATTGTCGATGAAGCCTCCATGTTGGATACCGCATTGATGCTGCAACTTTTGAAAGCGGTCAAAACCGGCGCGCGCGTGAT
TCTGCTGGGCGATGAAAACCAGCTCCCGTCCGTCGGAATCGGGGCGGTGCTGTCGGTTTTGTCGCAAAAAACCGTTTTGG
ACGGAGAAACGCACCAAAGGCTGGCCGGTTTCCTTCCGGAACACGGTTTCAGCGTCAGCGCAAATCCGCCCGTGTTGGCG
CAAAACACCGCCCATCTGTCGTTCAGCCACCGCTTCGGCGACAACAGCGGCATCGGCTGCCTTGCCCGTGCCGCCGTATC
GGGCGATGAAGGGGCGTGGGCATTGTTTGACCGGTTTCCGGACGAACTGGAACATTCGGAATGCAGTCCGAATGCTCGGG
TCGAAAGGTTGTACCGGGCGCACAAAGCCTATTGGCAGGCGGTAAAAGACGGCAATATCGAAGCCGCATACGCAGGCATC
TCGGATATCGTGGTTCTGGCAGCTTGGCGGCAGGATGCGGAAGACTTCAACGAAGCCTATTGCAGCTATGTACGCCGCAA
AATGAACATACCGGAACATTTGGCCTATTTCGCCGGAGAGCCGATTATGATCAGACAGAACGACTACGCGCTTGAGCTGT
TCAACGGCGACATCGGACTGATTATGGAAGATGTCGGACGGCAGGGCAGCCTTGCCGCCTATTTTGCCGATGCGGACGGA
TTTAAAAAGGTAGCGGTAAGCTGCCTGCCCGAATTTGAACCCGCATTCGCCATGACCGTCCACAAAAGCCAAGGTTCGGA
ATATCGGGAAGTCTGGCTGCTGCCGCCTTCCGACGCACCTTCGGACGAAGGGGACGATGCATTGTCCGGATTGAGTAAGG
AGCTGTTATATACCGCCATTACCCGCGCCAGGGAAAAATTCGTATTTTTCGGCGGCAAAAAGACATTTTGTCAGGCGGTA
AACACCGTCAAAGTCCGTCAGACGGCGTTGGGCAGTATGCTTGAGCGGGTATTTTCACAAGAATAA
ATGGAACTGCAGACAGATGAATTTGCCCAAGCGGCGGCAAGGGCGGCAATCCGTTTTTTGGAACGCTATGCGGGTTCGGG
CAACGAAGTGCTTGCAAACTGTACCGAACGCCTGTTTCAGGCATTGCAAAACGGTCATTCGTTTATCCGTTTGAGCGGGG
ACGAGGCTGACGCGCTGTCGGCACTCGCACCCGTGGTCGGAACATCCGCCGCGCCTTTGATTTTGGAAGGCAGAAGGCTG
TTTTTGGGCAGGATGTGGCAGTTGGAATACGATTTGGCTGCCGAAATAAAACGCTTGGCGGCAGCCGGCACGTCCGCCCC
CGACGCGGCAGGCGCGCGGCAAAACCTCGCAAAATGGTTTCAAGGCGCGGGAAGCGAAGGACAGCGCGATGCGGCCGCCT
TGGCACTGTTGCAGTTTTTTATGGTGATTACCGGAGGGCCGGGAACGGGCAAAACGACAACGGTTGCCAAACTGCTGGCA
CTGATTTGCGGTGAAAACGAAAATCTTCCCCATATCGCGCTTGCCGCACCGACGGGCAAAGCGGCGGCACATATGGCGCG
CGCGCTGCACCGTGCAATCAACGGTTTTGACGCGCCGGAGGCCGTCCGCCGCCATTTGCTCAAACTGGAAGGGCAAACCG
TCCACCGACTGCTTAAGCTGAGCCCGCCCAAAATGCAGGCGGCGTTCGACCATATCCGTCCGCTGCCGTTCGACGTGCTG
ATTGTCGATGAAGCCTCCATGTTGGATACCGCATTGATGCTGCAACTTTTGAAAGCGGTCAAAACCGGCGCGCGCGTGAT
TCTGCTGGGCGATGAAAACCAGCTCCCGTCCGTCGGAATCGGGGCGGTGCTGTCGGTTTTGTCGCAAAAAACCGTTTTGG
ACGGAGAAACGCACCAAAGGCTGGCCGGTTTCCTTCCGGAACACGGTTTCAGCGTCAGCGCAAATCCGCCCGTGTTGGCG
CAAAACACCGCCCATCTGTCGTTCAGCCACCGCTTCGGCGACAACAGCGGCATCGGCTGCCTTGCCCGTGCCGCCGTATC
GGGCGATGAAGGGGCGTGGGCATTGTTTGACCGGTTTCCGGACGAACTGGAACATTCGGAATGCAGTCCGAATGCTCGGG
TCGAAAGGTTGTACCGGGCGCACAAAGCCTATTGGCAGGCGGTAAAAGACGGCAATATCGAAGCCGCATACGCAGGCATC
TCGGATATCGTGGTTCTGGCAGCTTGGCGGCAGGATGCGGAAGACTTCAACGAAGCCTATTGCAGCTATGTACGCCGCAA
AATGAACATACCGGAACATTTGGCCTATTTCGCCGGAGAGCCGATTATGATCAGACAGAACGACTACGCGCTTGAGCTGT
TCAACGGCGACATCGGACTGATTATGGAAGATGTCGGACGGCAGGGCAGCCTTGCCGCCTATTTTGCCGATGCGGACGGA
TTTAAAAAGGTAGCGGTAAGCTGCCTGCCCGAATTTGAACCCGCATTCGCCATGACCGTCCACAAAAGCCAAGGTTCGGA
ATATCGGGAAGTCTGGCTGCTGCCGCCTTCCGACGCACCTTCGGACGAAGGGGACGATGCATTGTCCGGATTGAGTAAGG
AGCTGTTATATACCGCCATTACCCGCGCCAGGGAAAAATTCGTATTTTTCGGCGGCAAAAAGACATTTTGTCAGGCGGTA
AACACCGTCAAAGTCCGTCAGACGGCGTTGGGCAGTATGCTTGAGCGGGTATTTTCACAAGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| recD | Neisseria gonorrhoeae strain FA1090 |
99.828 |
100 |
0.998 |