Detailed information NTG0069188

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EP178_RS09880
• Genome accession: NZ_AP018377
• Coordinates: 1685513..1686373 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FC428
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1680513..1691373

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EP178_RS09860 (NgFC428_01735)	dapD	1681023..1681844 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
EP178_RS09865 (NgFC428_01736)	pgi	1682054..1683697 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
EP178_RS09875 (NgFC428_01737)	pilG	1684207..1685439 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
EP178_RS09880 (NgFC428_01738)	pilD	1685513..1686373 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
EP178_RS09885 (NgFC428_01739)	coaE	1686370..1687002 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
EP178_RS09890 (NgFC428_01740)	-	1686995..1687204 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
EP178_RS09895 (NgFC428_01741)	pilF	1687290..1688966 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EP178_RS09910 (NgFC428_01743)	-	1689304..1689750 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
EP178_RS09915 (NgFC428_01744)	-	1689754..1690728 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
EP178_RS09925 (NgFC428_01745)	rplU	1690952..1691260 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=69188 EP178_RS09880 WP_003689814.1 1685513..1686373(+) (pilD) [Neisseria gonorrhoeae strain FC428]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=69188 EP178_RS09880 WP_003689814.1 1685513..1686373(+) (pilD) [Neisseria gonorrhoeae strain FC428]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441