Detailed information NTG0690768

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M8962_RS06190
• Genome accession: NZ_CP097591
• Coordinates: 1363886..1365049 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UA0188
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1358886..1370049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8962_RS06170	-	1359287..1360483 (+)	1197	WP_012118575.1	glycosyltransferase	-
M8962_RS06175	-	1360616..1361692 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
M8962_RS06180	-	1361791..1363011 (-)	1221	WP_012118574.1	LCP family protein	-
M8962_RS06185	-	1363016..1363663 (-)	648	WP_007614107.1	YigZ family protein	-
M8962_RS06190	degS	1363886..1365049 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
M8962_RS06195	degU	1365126..1365815 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M8962_RS06200	-	1365913..1366761 (+)	849	WP_003151387.1	DegV family protein	-
M8962_RS06205	comFA	1366869..1368254 (+)	1386	WP_012118573.1	DEAD/DEAH box helicase	Machinery gene
M8962_RS06210	-	1368312..1368596 (+)	285	WP_007407481.1	competence protein ComFB	-
M8962_RS06215	comFC	1368602..1369291 (+)	690	WP_197197403.1	double zinc ribbon domain-containing protein	Machinery gene
M8962_RS06220	-	1369365..1369784 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=690768 M8962_RS06190 WP_007407484.1 1363886..1365049(+) (degS) [Bacillus velezensis strain UA0188]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=690768 M8962_RS06190 WP_007407484.1 1363886..1365049(+) (degS) [Bacillus velezensis strain UA0188]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951