Detailed information NTG0690586

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: M8961_RS14810
• Genome accession: NZ_CP097588
• Coordinates: 2989381..2990544 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UA0323
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2984381..2995544

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8961_RS14780	-	2984646..2985065 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
M8961_RS14785	comFC	2985139..2985828 (-)	690	WP_197197403.1	double zinc ribbon domain-containing protein	Machinery gene
M8961_RS14790	-	2985834..2986118 (-)	285	WP_007407481.1	competence protein ComFB	-
M8961_RS14795	comFA	2986176..2987561 (-)	1386	WP_012118573.1	DEAD/DEAH box helicase	Machinery gene
M8961_RS14800	-	2987669..2988517 (-)	849	WP_003151387.1	DegV family protein	-
M8961_RS14805	degU	2988615..2989304 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
M8961_RS14810	degS	2989381..2990544 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
M8961_RS14815	-	2990767..2991414 (+)	648	WP_007614107.1	YigZ family protein	-
M8961_RS14820	-	2991419..2992639 (+)	1221	WP_012118574.1	LCP family protein	-
M8961_RS14825	-	2992738..2993814 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
M8961_RS14830	-	2993947..2995143 (-)	1197	WP_012118575.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=690586 M8961_RS14810 WP_007407484.1 2989381..2990544(-) (degS) [Bacillus velezensis strain UA0323]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=690586 M8961_RS14810 WP_007407484.1 2989381..2990544(-) (degS) [Bacillus velezensis strain UA0323]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951