Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STO1_RS01795 Genome accession   NZ_AP018338
Coordinates   354946..355635 (+) Length   229 a.a.
NCBI ID   WP_000517997.1    Uniprot ID   A0A224A3I0
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 349946..360635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS01770 (STO1_003470) gpsB 350009..350335 (+) 327 WP_007520632.1 cell division regulator GpsB -
  STO1_RS01780 (STO1_003480) - 350823..351995 (+) 1173 WP_084917717.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  STO1_RS01785 (STO1_003490) mapZ 351992..353434 (+) 1443 WP_061588438.1 cell division site-positioning protein MapZ -
  STO1_RS01790 (STO1_003500) gndA 353510..354934 (+) 1425 WP_096421690.1 NADP-dependent phosphogluconate dehydrogenase -
  STO1_RS01795 (STO1_003510) covR 354946..355635 (+) 690 WP_000517997.1 response regulator transcription factor Regulator
  STO1_RS01800 (STO1_003520) cbpF 355735..356730 (+) 996 WP_061588437.1 choline-binding protein CbpF -
  STO1_RS01805 (STO1_003530) mvk 356847..357725 (+) 879 WP_000163309.1 mevalonate kinase -
  STO1_RS01810 (STO1_003540) mvaD 357707..358660 (+) 954 WP_096421692.1 diphosphomevalonate decarboxylase -
  STO1_RS01815 (STO1_003550) - 358647..359654 (+) 1008 WP_096421694.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26737.86 Da        Isoelectric Point: 7.4647

>NTDB_id=69045 STO1_RS01795 WP_000517997.1 354946..355635(+) (covR) [Streptococcus oralis subsp. tigurinus strain osk_001]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVDEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=69045 STO1_RS01795 WP_000517997.1 354946..355635(+) (covR) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATTTAGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTAGATGAAGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACGGACTATGACTTGATTTTACTGAATG
CTCATCTGGGGGATATGACGGCCCAGGATTTTGCAGACAAGCTGAGTCGGACAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGTGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTTGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATAATCTGGTAGCCCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATTGACCAACACTGTAGTCAGATGAAAGTTC
CAACGTCTTACCGCAACCTACGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTCTTGGCTACTCTCATGGGAAGCAAGAAAGTCTTGACTCGTGAGCAGTTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A224A3I0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment