Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   M8286_RS07715 Genome accession   NZ_CP097577
Coordinates   1586089..1586778 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1581089..1591778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS07690 (M8286_07815) - 1581855..1583006 (-) 1152 WP_275600836.1 replication initiation/membrane attachment protein -
  M8286_RS07695 (M8286_07820) nrdR 1582993..1583484 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  M8286_RS07700 (M8286_07825) - 1583556..1584686 (-) 1131 WP_012027644.1 AI-2E family transporter -
  M8286_RS07705 (M8286_10250) - 1584791..1585678 (-) 888 WP_358636213.1 IS3 family transposase -
  M8286_RS07710 (M8286_07840) - 1585675..1585995 (-) 321 WP_275600840.1 transposase -
  M8286_RS07715 (M8286_07845) covR 1586089..1586778 (-) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  M8286_RS07720 (M8286_07850) gndA 1586860..1588287 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  M8286_RS07725 (M8286_07855) - 1588384..1588923 (-) 540 WP_014736258.1 DUF177 domain-containing protein -
  M8286_RS07730 (M8286_07860) trxB 1588933..1589850 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  M8286_RS07735 (M8286_07865) - 1589864..1590088 (-) 225 WP_002936682.1 DUF4059 family protein -
  M8286_RS07740 (M8286_07870) - 1590106..1591449 (-) 1344 WP_024406634.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=690345 M8286_RS07715 WP_012027645.1 1586089..1586778(-) (covR) [Streptococcus suis strain 3112]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=690345 M8286_RS07715 WP_012027645.1 1586089..1586778(-) (covR) [Streptococcus suis strain 3112]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGATAATAACTGTAAGCAGGTTCACATGC
ATGCAGCCTACCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACTCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432