Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   M8286_RS04805 Genome accession   NZ_CP097577
Coordinates   977995..979221 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain 3112     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 972995..984221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS04780 (M8286_04810) - 973313..974626 (-) 1314 WP_275601661.1 excalibur calcium-binding domain-containing protein -
  M8286_RS04785 (M8286_04815) - 974761..974943 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  M8286_RS04790 (M8286_04820) lepA 974990..976822 (-) 1833 WP_275601662.1 translation elongation factor 4 -
  M8286_RS04795 (M8286_04825) ndk 976918..977331 (-) 414 WP_275601663.1 nucleoside-diphosphate kinase -
  M8286_RS04800 (M8286_04830) yihA 977354..977941 (-) 588 WP_275601664.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  M8286_RS04805 (M8286_04835) clpX 977995..979221 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  M8286_RS04810 (M8286_04840) - 979419..979931 (-) 513 WP_275601666.1 dihydrofolate reductase -
  M8286_RS04815 (M8286_04845) - 980106..980945 (-) 840 WP_136670590.1 thymidylate synthase -
  M8286_RS04820 (M8286_04850) - 980997..981299 (-) 303 WP_024417934.1 hypothetical protein -
  M8286_RS04825 (M8286_04855) - 981715..982674 (-) 960 WP_105121190.1 ROK family glucokinase -
  M8286_RS04830 (M8286_04860) - 982770..983105 (-) 336 WP_275601667.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=690339 M8286_RS04805 WP_002934974.1 977995..979221(-) (clpX) [Streptococcus suis strain 3112]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=690339 M8286_RS04805 WP_002934974.1 977995..979221(-) (clpX) [Streptococcus suis strain 3112]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
TGGGAACAATGTCTTCATTTGTAATGAATGCGTGGAACTAGCACAGGAAATCATTCGCGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTAGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAGGATAGCCGGGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGTCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTTGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGTGCTCGCGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574