Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   M8789_RS02395 Genome accession   NZ_CP097571
Coordinates   523391..523960 (+) Length   189 a.a.
NCBI ID   WP_250164390.1    Uniprot ID   -
Organism   Staphylococcus aureus strain V40     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 518391..528960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8789_RS02370 (M8789_02370) cysE 519604..520251 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  M8789_RS02375 (M8789_02375) cysS 520235..521635 (+) 1401 WP_250164389.1 cysteine--tRNA ligase -
  M8789_RS02380 (M8789_02380) - 521628..522032 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  M8789_RS02385 (M8789_02385) rlmB 522040..522786 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  M8789_RS02390 (M8789_02390) - 522786..523310 (+) 525 WP_000664738.1 NYN domain-containing protein -
  M8789_RS02395 (M8789_02395) sigH 523391..523960 (+) 570 WP_250164390.1 sigma-70 family RNA polymerase sigma factor Regulator
  M8789_RS02400 (M8789_02400) rpmG 524075..524218 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  M8789_RS02405 (M8789_02405) secE 524274..524456 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  M8789_RS02410 (M8789_02410) nusG 524469..525017 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  M8789_RS02415 (M8789_02415) rplK 525198..525620 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  M8789_RS02420 (M8789_02420) rplA 525828..526520 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  M8789_RS02425 (M8789_02425) rplJ 526792..527292 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  M8789_RS02430 (M8789_02430) rplL 527335..527703 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  M8789_RS02435 (M8789_02435) - 527878..528486 (+) 609 WP_000020308.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23025.89 Da        Isoelectric Point: 9.6924

>NTDB_id=690174 M8789_RS02395 WP_250164390.1 523391..523960(+) (sigH) [Staphylococcus aureus strain V40]
MKYDLTTQGSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGDQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=690174 M8789_RS02395 WP_250164390.1 523391..523960(+) (sigH) [Staphylococcus aureus strain V40]
TTGAAATATGATTTGACAACTCAAGGCAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGACCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGCGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974