Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   OTU45_RS08700 Genome accession   NZ_CP113114
Coordinates   1709020..1709697 (-) Length   225 a.a.
NCBI ID   WP_016397619.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1704020..1714697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS08675 (OTU45_08675) - 1704192..1704821 (-) 630 Protein_1722 NAD(P)-dependent oxidoreductase -
  OTU45_RS08680 (OTU45_08680) - 1705060..1705423 (+) 364 Protein_1723 hypothetical protein -
  OTU45_RS08685 (OTU45_08685) - 1705680..1706003 (+) 324 WP_025172496.1 hypothetical protein -
  OTU45_RS08690 (OTU45_08690) thrS 1706061..1708004 (+) 1944 WP_025172495.1 threonine--tRNA ligase -
  OTU45_RS08695 (OTU45_08695) - 1708053..1709027 (-) 975 WP_000887964.1 HAMP domain-containing histidine kinase -
  OTU45_RS08700 (OTU45_08700) braR 1709020..1709697 (-) 678 WP_016397619.1 response regulator transcription factor Regulator
  OTU45_RS08705 (OTU45_08705) - 1709853..1710926 (+) 1074 WP_050082919.1 DUF2974 domain-containing protein -
  OTU45_RS08710 (OTU45_08710) - 1711017..1711319 (-) 303 WP_000281608.1 hypothetical protein -
  OTU45_RS08715 (OTU45_08715) - 1711387..1711824 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  OTU45_RS08720 (OTU45_08720) - 1711900..1712742 (-) 843 WP_000160958.1 metallophosphoesterase family protein -
  OTU45_RS08725 (OTU45_08725) - 1712854..1713504 (+) 651 WP_000188504.1 metal-dependent transcriptional regulator -
  OTU45_RS08730 (OTU45_08730) - 1713681..1714358 (+) 678 WP_000260179.1 nicotinamide mononucleotide transporter family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25918.07 Da        Isoelectric Point: 5.1362

>NTDB_id=689694 OTU45_RS08700 WP_016397619.1 1709020..1709697(-) (braR) [Streptococcus pneumoniae strain NP1]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLIDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=689694 OTU45_RS08700 WP_016397619.1 1709020..1709697(-) (braR) [Streptococcus pneumoniae strain NP1]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATAGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCAGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAACGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369