Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   OTU45_RS01400 Genome accession   NZ_CP113114
Coordinates   275254..275694 (-) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP1     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 270254..280694
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU45_RS01380 (OTU45_01380) nrdI 270756..271226 (+) 471 WP_000849622.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  OTU45_RS01385 (OTU45_01385) - 271519..272781 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  OTU45_RS01390 (OTU45_01390) - 273026..274372 (+) 1347 WP_001826500.1 IS1380-like element ISSpn5 family transposase -
  OTU45_RS01395 (OTU45_01395) - 274799..275257 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  OTU45_RS01400 (OTU45_01400) brsR 275254..275694 (-) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  OTU45_RS01405 (OTU45_01405) hexB 276050..277999 (+) 1950 WP_000018164.1 DNA mismatch repair endonuclease MutL Machinery gene
  OTU45_RS01410 (OTU45_01410) ribE 278323..278790 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  OTU45_RS01415 (OTU45_01415) - 278791..279996 (-) 1206 WP_267749957.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  OTU45_RS01420 (OTU45_01420) ribE 280016..280651 (-) 636 WP_267749958.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=689638 OTU45_RS01400 WP_000861968.1 275254..275694(-) (brsR) [Streptococcus pneumoniae strain NP1]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=689638 OTU45_RS01400 WP_000861968.1 275254..275694(-) (brsR) [Streptococcus pneumoniae strain NP1]
ATGAAAGTAGAATTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
TCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363