Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   M5J22_RS14985 Genome accession   NZ_CP097326
Coordinates   3067451..3068095 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain GUCC45     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3062451..3073095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5J22_RS14950 (M5J22_14950) - 3063636..3064067 (+) 432 WP_003152066.1 Na(+)/H(+) antiporter subunit B -
  M5J22_RS14955 (M5J22_14955) - 3064067..3064408 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  M5J22_RS14960 (M5J22_14960) - 3064401..3065882 (+) 1482 WP_043867375.1 Na+/H+ antiporter subunit D -
  M5J22_RS14965 (M5J22_14965) - 3065888..3066364 (+) 477 WP_003152059.1 Na+/H+ antiporter subunit E -
  M5J22_RS14970 (M5J22_14970) - 3066364..3066648 (+) 285 WP_003152057.1 Na(+)/H(+) antiporter subunit F1 -
  M5J22_RS14975 (M5J22_14975) mnhG 3066632..3067006 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  M5J22_RS14980 (M5J22_14980) - 3067046..3067429 (-) 384 WP_003152054.1 hotdog fold thioesterase -
  M5J22_RS14985 (M5J22_14985) comA 3067451..3068095 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  M5J22_RS14990 (M5J22_14990) - 3068176..3070481 (-) 2306 Protein_2896 sensor histidine kinase -
  M5J22_RS14995 (M5J22_14995) comX 3070500..3070676 (-) 177 WP_044052947.1 competence pheromone ComX -
  M5J22_RS15000 (M5J22_15000) - 3070691..3071587 (-) 897 WP_017419425.1 polyprenyl synthetase family protein -
  M5J22_RS15005 (M5J22_15005) degQ 3071718..3071858 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  M5J22_RS15010 (M5J22_15010) - 3072324..3072665 (+) 342 WP_003152040.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=688489 M5J22_RS14985 WP_003152052.1 3067451..3068095(-) (comA) [Bacillus velezensis strain GUCC45]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=688489 M5J22_RS14985 WP_003152052.1 3067451..3068095(-) (comA) [Bacillus velezensis strain GUCC45]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATCGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAATAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864