Detailed information NTG0688027

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: M3N36_RS02155
• Genome accession: NZ_CP097251
• Coordinates: 414793..415794 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 409793..420794

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3N36_RS02130 (M3N36_02130)	-	410467..411150 (-)	684	WP_030127180.1	DUF969 domain-containing protein	-
M3N36_RS02135 (M3N36_02135)	-	411361..412287 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
M3N36_RS02140 (M3N36_02140)	-	412432..412809 (-)	378	WP_002985686.1	VOC family protein	-
M3N36_RS02145 (M3N36_02145)	-	412820..413485 (-)	666	WP_030127181.1	NAD(P)H-dependent oxidoreductase	-
M3N36_RS02150 (M3N36_02150)	-	413534..414619 (-)	1086	WP_030127182.1	Xaa-Pro peptidase family protein	-
M3N36_RS02155 (M3N36_02155)	ccpA	414793..415794 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
M3N36_RS02160 (M3N36_02160)	-	415925..416923 (+)	999	WP_030127183.1	glycosyltransferase family 4 protein	-
M3N36_RS02165 (M3N36_02165)	-	416925..418259 (+)	1335	WP_030127184.1	glycosyltransferase family 4 protein	-
M3N36_RS02170 (M3N36_02170)	thrS	418681..420624 (+)	1944	WP_030127185.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=688027 M3N36_RS02155 WP_002985680.1 414793..415794(+) (ccpA) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=688027 M3N36_RS02155 WP_002985680.1 414793..415794(+) (ccpA) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCTAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559