Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OS077_RS14240 Genome accession   NZ_CP113016
Coordinates   2841768..2842391 (-) Length   207 a.a.
NCBI ID   WP_001045130.1    Uniprot ID   -
Organism   Staphylococcus aureus strain Azir     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2836768..2847391
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS077_RS14215 - 2837147..2838343 (-) 1197 WP_000238221.1 metallophosphoesterase family protein -
  OS077_RS14220 - 2838640..2838738 (-) 99 WP_031774968.1 hypothetical protein -
  OS077_RS14225 - 2839232..2839576 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  OS077_RS14230 - 2839645..2840769 (-) 1125 WP_000992523.1 DUF445 domain-containing protein -
  OS077_RS14235 xdrA 2840948..2841412 (-) 465 WP_000375864.1 XRE family transcriptional regulator XdrA -
  OS077_RS14240 vraR 2841768..2842391 (-) 624 WP_001045130.1 response regulator Regulator
  OS077_RS14245 - 2842413..2843525 (-) 1113 WP_031590025.1 GAF domain-containing sensor histidine kinase -
  OS077_RS14250 - 2843688..2844509 (+) 822 WP_000669376.1 RluA family pseudouridine synthase -
  OS077_RS14255 fumC 2844961..2846346 (-) 1386 WP_000116229.1 class II fumarate hydratase -
  OS077_RS14260 - 2846542..2846937 (-) 396 WP_000901023.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23953.60 Da        Isoelectric Point: 5.3526

>NTDB_id=687594 OS077_RS14240 WP_001045130.1 2841768..2842391(-) (vraR) [Staphylococcus aureus strain Azir]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPDMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=687594 OS077_RS14240 WP_001045130.1 2841768..2842391(-) (vraR) [Staphylococcus aureus strain Azir]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGACATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATTGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.063

100

0.411
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377