Detailed information NTG0687217

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: M3M42_RS13110
• Genome accession: NZ_CP097114
• Coordinates: 2628920..2629807 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain JP18269
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2623920..2634807

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3M42_RS13080 (M3M42_13065)	-	2623939..2624031 (+)	93	WP_010956583.1	hypothetical protein	-
M3M42_RS13085 (M3M42_13070)	-	2624139..2624636 (-)	498	WP_001065268.1	glutathione peroxidase	-
M3M42_RS13090 (M3M42_13075)	-	2624646..2624906 (-)	261	WP_001789910.1	hypothetical protein	-
M3M42_RS13095 (M3M42_13080)	-	2625288..2625401 (-)	114	WP_011447078.1	hypothetical protein	-
M3M42_RS13100 (M3M42_13085)	-	2626060..2628060 (-)	2001	WP_000776751.1	ABC transporter permease	-
M3M42_RS13105 (M3M42_13090)	-	2628057..2628812 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
M3M42_RS13110 (M3M42_13095)	braS	2628920..2629807 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
M3M42_RS13115 (M3M42_13100)	braR	2629818..2630483 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
M3M42_RS13120 (M3M42_13105)	-	2630509..2630709 (-)	201	WP_000604728.1	hypothetical protein	-
M3M42_RS13125 (M3M42_13110)	-	2630907..2632331 (+)	1425	WP_000953744.1	alkaline phosphatase	-
M3M42_RS13610	-	2632391..2632492 (-)	102	WP_000731972.1	SE2200 family small protein	-
M3M42_RS13135 (M3M42_13120)	-	2632614..2633069 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
M3M42_RS13140 (M3M42_13125)	-	2633314..2634075 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=687217 M3M42_RS13110 WP_000143419.1 2628920..2629807(-) (braS) [Staphylococcus aureus strain JP18269]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=687217 M3M42_RS13110 WP_000143419.1 2628920..2629807(-) (braS) [Staphylococcus aureus strain JP18269]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997