Detailed information NTG0068709

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: KK0981_RS10045
• Genome accession: NZ_AP017971
• Coordinates: 1867242..1868279 (-)
• Length: 345 a.a.
• NCBI ID: WP_001842811.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain KK0981
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1862242..1873279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KK0981_RS10020 (KK0981_39570)	-	1862981..1864312 (-)	1332	WP_000390042.1	hemolysin family protein	-
KK0981_RS10025 (KK0981_39580)	endA	1864603..1865427 (-)	825	WP_001036790.1	DNA-entry nuclease EndA	Machinery gene
KK0981_RS10030 (KK0981_39590)	-	1865466..1865654 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
KK0981_RS10035 (KK0981_39600)	murA	1865647..1866930 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
KK0981_RS10040 (KK0981_39610)	-	1866954..1867184 (-)	231	WP_000250384.1	DUF1146 family protein	-
KK0981_RS10045 (KK0981_39620)	sepM	1867242..1868279 (-)	1038	WP_001842811.1	SepM family pheromone-processing serine protease	Regulator
KK0981_RS10050 (KK0981_39630)	coaD	1868263..1868751 (-)	489	WP_001280753.1	pantetheine-phosphate adenylyltransferase	-
KK0981_RS10055 (KK0981_39640)	rsmD	1868741..1869280 (-)	540	WP_000706959.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
KK0981_RS10060 (KK0981_39650)	asnA	1869345..1870337 (-)	993	WP_000747990.1	aspartate--ammonia ligase	-
KK0981_RS10070 (KK0981_39660)	-	1870449..1871132 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
KK0981_RS10075 (KK0981_39670)	-	1871188..1871928 (-)	741	WP_000152678.1	TrmH family RNA methyltransferase	-
KK0981_RS10080 (KK0981_39680)	-	1871962..1872240 (+)	279	WP_001174613.1	acylphosphatase	-
KK0981_RS10085 (KK0981_39690)	yidC	1872318..1873244 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37563.65 Da
• Isoelectric Point: 5.0724

>NTDB_id=68709 KK0981_RS10045 WP_001842811.1 1867242..1868279(-) (sepM) [Streptococcus pneumoniae strain KK0981]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFLTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=68709 KK0981_RS10045 WP_001842811.1 1867242..1868279(-) (sepM) [Streptococcus pneumoniae strain KK0981]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTTAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588