Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   KK0981_RS01920 Genome accession   NZ_AP017971
Coordinates   345927..346616 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain KK0981     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 340927..351616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KK0981_RS01895 (KK0981_23870) gpsB 341024..341365 (+) 342 WP_000200644.1 cell division regulator GpsB -
  KK0981_RS01905 (KK0981_23880) - 341851..343008 (+) 1158 WP_000711398.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  KK0981_RS01910 (KK0981_23890) mapZ 343021..344415 (+) 1395 WP_050201456.1 cell division site-positioning protein MapZ -
  KK0981_RS01915 (KK0981_23900) gndA 344491..345915 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  KK0981_RS01920 (KK0981_23910) covR 345927..346616 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  KK0981_RS01925 (KK0981_23920) cbpC 346714..347679 (+) 966 WP_050201455.1 choline-binding protein CbpC -
  KK0981_RS01930 (KK0981_23930) cbpJ 347698..348696 (+) 999 WP_050209859.1 choline-binding protein CbpJ -
  KK0981_RS01935 (KK0981_23940) - 348814..350046 (-) 1233 WP_050201453.1 MFS transporter -
  KK0981_RS01940 (KK0981_23950) - 350089..350508 (-) 420 WP_001831975.1 lanthionine synthetase -
  KK0981_RS12645 - 350576..350913 (-) 338 Protein_361 lantibiotic-modifying protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=68666 KK0981_RS01920 WP_000518018.1 345927..346616(+) (covR) [Streptococcus pneumoniae strain KK0981]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=68666 KK0981_RS01920 WP_000518018.1 345927..346616(+) (covR) [Streptococcus pneumoniae strain KK0981]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment