Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ORM93_RS01810 Genome accession   NZ_CP111098
Coordinates   310504..311160 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain RM6067W     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 305504..316160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ORM93_RS01775 (ORM93_01765) dcyD 306383..307369 (+) 987 WP_001128225.1 D-cysteine desulfhydrase -
  ORM93_RS01780 (ORM93_01770) tcyL 307384..308052 (+) 669 WP_001158226.1 cystine ABC transporter permease -
  ORM93_RS01785 (ORM93_01775) tcyN 308049..308801 (+) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ORM93_RS01790 (ORM93_01780) sdiA 309031..309753 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  ORM93_RS01795 (ORM93_01785) yecF 309821..310045 (-) 225 WP_000106478.1 DUF2594 family protein YecF -
  ORM93_RS01800 (ORM93_01790) yecU 310032..310208 (-) 177 WP_001302050.1 protein YecU -
  ORM93_RS01805 - 310246..310362 (-) 117 WP_001302039.1 hypothetical protein -
  ORM93_RS01810 (ORM93_01795) letA 310504..311160 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ORM93_RS01815 (ORM93_01800) uvrC 311157..312989 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ORM93_RS01820 (ORM93_01805) pgsA 313046..313594 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ORM93_RS01840 (ORM93_01825) - 314586..314867 (+) 282 WP_001303543.1 hypothetical protein -
  ORM93_RS01845 (ORM93_01830) - 314888..315082 (+) 195 WP_115801851.1 hypothetical protein -
  ORM93_RS01850 (ORM93_01835) - 315024..315191 (+) 168 Protein_358 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=686607 ORM93_RS01810 WP_000611328.1 310504..311160(+) (letA) [Escherichia coli strain RM6067W]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=686607 ORM93_RS01810 WP_000611328.1 310504..311160(+) (letA) [Escherichia coli strain RM6067W]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482