Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M2916_RS12355 Genome accession   NZ_CP097027
Coordinates   2505853..2507094 (-) Length   413 a.a.
NCBI ID   WP_002298209.1    Uniprot ID   -
Organism   Enterococcus faecium strain AT44     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2500853..2512094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2916_RS12340 (M2916_12340) proC 2501846..2502652 (+) 807 WP_002298207.1 pyrroline-5-carboxylate reductase -
  M2916_RS12345 (M2916_12345) rny 2502731..2504287 (-) 1557 WP_002287336.1 ribonuclease Y -
  M2916_RS12350 (M2916_12350) recA 2504698..2505744 (-) 1047 WP_002298208.1 recombinase RecA Machinery gene
  M2916_RS12355 (M2916_12355) cinA 2505853..2507094 (-) 1242 WP_002298209.1 competence/damage-inducible protein A Machinery gene
  M2916_RS12360 (M2916_12360) pgsA 2507334..2507912 (-) 579 WP_002298210.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M2916_RS12365 (M2916_12365) - 2508121..2509044 (-) 924 WP_002287423.1 RodZ domain-containing protein -
  M2916_RS12370 (M2916_12370) - 2509780..2511066 (-) 1287 WP_002287425.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45457.84 Da        Isoelectric Point: 4.6507

>NTDB_id=686349 M2916_RS12355 WP_002298209.1 2505853..2507094(-) (cinA) [Enterococcus faecium strain AT44]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLVYFETTHRKMTKNNLQQSQIIEGGIPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=686349 M2916_RS12355 WP_002298209.1 2505853..2507094(-) (cinA) [Enterococcus faecium strain AT44]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGTATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATCATCGAAGGCGGGATTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAAACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-410)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.429

100

0.523
  cinA Streptococcus pneumoniae TIGR4

51.19

100

0.521
  cinA Streptococcus mitis NCTC 12261

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Streptococcus pneumoniae R6

50.952

100

0.518
  cinA Streptococcus pneumoniae Rx1

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.952

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

41.787

100

0.419