Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ORI88_RS08420 Genome accession   NZ_CP110999
Coordinates   1747844..1748500 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain J53-p133     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1742844..1753500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ORI88_RS08390 (ORI88_08390) dcyD 1743723..1744709 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ORI88_RS08395 (ORI88_08395) tcyL 1744724..1745392 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ORI88_RS08400 (ORI88_08400) tcyN 1745389..1746141 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ORI88_RS08405 (ORI88_08405) sdiA 1746371..1747093 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  ORI88_RS08410 (ORI88_08410) yecF 1747161..1747385 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ORI88_RS08415 (ORI88_08415) yecU 1747372..1747548 (-) 177 WP_000590347.1 protein YecU -
  ORI88_RS24570 - 1747631..1747702 (-) 72 Protein_1645 transcriptional regulator -
  ORI88_RS08420 (ORI88_08420) letA 1747844..1748500 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ORI88_RS08425 (ORI88_08425) uvrC 1748497..1750329 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ORI88_RS08430 (ORI88_08430) pgsA 1750386..1750934 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ORI88_RS08450 (ORI88_08450) yecA 1751584..1752249 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=686016 ORI88_RS08420 WP_000611335.1 1747844..1748500(+) (letA) [Escherichia coli strain J53-p133]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=686016 ORI88_RS08420 WP_000611335.1 1747844..1748500(+) (letA) [Escherichia coli strain J53-p133]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486