Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ORI30_RS03180 Genome accession   NZ_CP110996
Coordinates   623677..624333 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain XYEH3783     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 618677..629333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ORI30_RS03150 (ORI30_03150) yecA 619929..620594 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  ORI30_RS03170 (ORI30_03170) pgsA 621243..621791 (-) 549 WP_001538881.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ORI30_RS03175 (ORI30_03175) uvrC 621848..623680 (-) 1833 WP_001773939.1 excinuclease ABC subunit UvrC Machinery gene
  ORI30_RS03180 (ORI30_03180) letA 623677..624333 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ORI30_RS03185 (ORI30_03185) yecU 624629..624805 (+) 177 WP_001307856.1 protein YecU -
  ORI30_RS03190 (ORI30_03190) yecF 624792..625016 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ORI30_RS03195 (ORI30_03195) sdiA 625084..625806 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  ORI30_RS03200 (ORI30_03200) tcyN 626036..626788 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ORI30_RS03205 (ORI30_03205) tcyL 626785..627453 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ORI30_RS03210 (ORI30_03210) dcyD 627468..628454 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=685897 ORI30_RS03180 WP_000611328.1 623677..624333(-) (letA) [Escherichia coli strain XYEH3783]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=685897 ORI30_RS03180 WP_000611328.1 623677..624333(-) (letA) [Escherichia coli strain XYEH3783]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTTAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482