Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ORI33_RS09275 Genome accession   NZ_CP110978
Coordinates   1921358..1922014 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain XYEH3934     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1916358..1927014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ORI33_RS09245 (ORI33_09245) dcyD 1917237..1918223 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ORI33_RS09250 (ORI33_09250) tcyL 1918238..1918906 (+) 669 WP_266059056.1 cystine ABC transporter permease -
  ORI33_RS09255 (ORI33_09255) tcyN 1918903..1919655 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ORI33_RS09260 (ORI33_09260) sdiA 1919885..1920607 (+) 723 WP_063078868.1 transcriptional regulator SdiA -
  ORI33_RS09265 (ORI33_09265) yecF 1920675..1920899 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ORI33_RS09270 (ORI33_09270) yecU 1920886..1921062 (-) 177 WP_000590344.1 protein YecU -
  ORI33_RS23935 - 1921100..1921216 (-) 117 WP_001302039.1 hypothetical protein -
  ORI33_RS09275 (ORI33_09275) letA 1921358..1922014 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ORI33_RS09280 (ORI33_09280) uvrC 1922011..1923843 (+) 1833 WP_266059057.1 excinuclease ABC subunit UvrC Machinery gene
  ORI33_RS09285 (ORI33_09285) pgsA 1923900..1924448 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ORI33_RS09305 (ORI33_09305) yecA 1925097..1925762 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=685767 ORI33_RS09275 WP_000611328.1 1921358..1922014(+) (letA) [Escherichia coli strain XYEH3934]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=685767 ORI33_RS09275 WP_000611328.1 1921358..1922014(+) (letA) [Escherichia coli strain XYEH3934]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482