Detailed information NTG0685447

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: SLV14N_RS16875
• Genome accession: NZ_CP110836
• Coordinates: 3934866..3935990 (+)
• Length: 374 a.a.
• NCBI ID: WP_026170238.1
• Uniprot ID: A0A640THM3
• Organism: Streptomyces sp. Je 1-4 4N24
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3929866..3940990

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SLV14N_RS16860 (SLV14N_003382)	-	3930416..3931279 (+)	864	WP_208681699.1	hypothetical protein	-
SLV14N_RS16865 (SLV14N_003383)	-	3931331..3933079 (-)	1749	WP_263269929.1	sigma-70 family RNA polymerase sigma factor	-
SLV14N_RS16870 (SLV14N_003384)	radA	3933328..3934740 (+)	1413	WP_263269931.1	DNA repair protein RadA	Machinery gene
SLV14N_RS16875 (SLV14N_003385)	disA	3934866..3935990 (+)	1125	WP_026170238.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
SLV14N_RS16880 (SLV14N_003386)	-	3936015..3936431 (-)	417	WP_263273189.1	pyridoxamine 5'-phosphate oxidase family protein	-
SLV14N_RS16885 (SLV14N_003387)	-	3936600..3937925 (-)	1326	WP_263269933.1	globin domain-containing protein	-
SLV14N_RS16890 (SLV14N_003388)	-	3938208..3938909 (+)	702	WP_263269935.1	response regulator transcription factor	-
SLV14N_RS16895 (SLV14N_003389)	-	3939016..3940650 (-)	1635	WP_263273191.1	GAF domain-containing protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40289.13 Da
• Isoelectric Point: 4.9306

>NTDB_id=685447 SLV14N_RS16875 WP_026170238.1 3934866..3935990(+) (disA) [Streptomyces sp. Je 1-4 4N24]
MAANDRASTPGRSGGSSSTESLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGFDKTVETMCTGGFVLDVEFTATRLR
ELCKLDGALVLDKDITKILRAGVQLVPDASIPTEETGTRHRTAQRVSIQAGFPVVSVSQSMRLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALAELDALSHTELLELPIVARALGYSGAPETLDSAVSPRGFRLLAKVPRLPGT
VIDRLVDHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=685447 SLV14N_RS16875 WP_026170238.1 3934866..3935990(+) (disA) [Streptomyces sp. Je 1-4 4N24]
GTGGCAGCCAACGACCGGGCATCGACTCCCGGCAGGTCCGGTGGCAGTTCCTCCACCGAGAGCCTGATGCGCGCCTCGCT
GAGCGCCGTCGCGCCCGGTACGGCCCTGCGCGACGGACTGGAGCGCATCCTGCGCGGCAACACCGGCGGACTGATCGTGC
TGGGCTTCGACAAGACCGTCGAAACCATGTGCACCGGCGGATTCGTCCTCGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGTGCGCTGGTCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGTGTCCAGCTGGTCCC
GGACGCCTCCATCCCGACGGAGGAGACCGGCACCCGCCACCGCACCGCCCAGCGCGTCTCCATCCAGGCCGGCTTCCCGG
TCGTCTCCGTCAGCCAGTCGATGCGCCTGATCGCCCTCTACGTCGACGGCGAGCGCCGCGTCCTGGAGGAGTCGGCCGCG
ATCCTCTCCCGCGCCAACCAGGCCCTGGCGACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTCGCCGGCACCCTCTC
CGCCCTGGAGATCGAGGACTTGGTGACGGTCCGCGATGTCACCGCGGTCGCCCAGCGCCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTCGTCGAACTCGGCACGGACGGCCGGCTGCTCGCCCTCCAGCTGGAGGAGCTGATCGCC
GGCGTGGAGCCCGAGCGGGAGCTGGTCGTCCGCGACTACGTCCCCGAGCCGACCGCCAAGCGCTCCCGTACGGTCGCCGA
GGCGCTCGCCGAGCTGGACGCCCTCAGCCACACCGAGCTCCTCGAACTCCCCATCGTGGCCCGCGCGCTGGGCTACAGCG
GCGCCCCCGAGACCCTGGACTCCGCGGTCTCGCCGCGCGGCTTCCGCCTGCTGGCGAAGGTCCCCCGGCTGCCCGGCACG
GTCATCGACCGCCTCGTCGACCACTTCGGCGGCCTGCAGAAGCTCCTCGCGGCCAGCGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGCGCCCGCTCGGTCCGCGAGGGCCTGTCGCGGCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-296)

3D structure

• AlphaFold DB: A0A640THM3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.665	92.513	0.422