Detailed information NTG0068513

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JP49775_RS13185
• Genome accession: NZ_AP017922
• Coordinates: 2621748..2622635 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain JP02758
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2616748..2627635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JP49775_RS13150	-	2616758..2616850 (+)	93	WP_031774855.1	hypothetical protein	-
JP49775_RS13155 (JP02758_2445)	-	2616958..2617455 (-)	498	WP_001065267.1	glutathione peroxidase	-
JP49775_RS13160 (JP02758_2446)	-	2617465..2617725 (-)	261	WP_072434822.1	hypothetical protein	-
JP49775_RS13170	-	2618107..2618220 (-)	114	WP_014937089.1	hypothetical protein	-
JP49775_RS13175 (JP02758_2447)	-	2618889..2620889 (-)	2001	WP_029549934.1	ABC transporter permease	-
JP49775_RS13180 (JP02758_2448)	-	2620886..2621641 (-)	756	WP_029549933.1	ABC transporter ATP-binding protein	-
JP49775_RS13185 (JP02758_2449)	braS	2621748..2622635 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JP49775_RS13190 (JP02758_2450)	braR	2622646..2623311 (-)	666	WP_029549932.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JP49775_RS13195 (JP02758_2451)	-	2623337..2623537 (-)	201	WP_029549931.1	hypothetical protein	-
JP49775_RS13200 (JP02758_2452)	-	2623734..2625158 (+)	1425	WP_029549930.1	alkaline phosphatase	-
JP49775_RS14200	-	2625218..2625319 (-)	102	WP_000731972.1	SE2200 family small protein	-
JP49775_RS13210 (JP02758_2453)	-	2625441..2625896 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JP49775_RS13215 (JP02758_2454)	-	2626140..2626901 (-)	762	WP_029549929.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=68513 JP49775_RS13185 WP_000143420.1 2621748..2622635(-) (braS) [Staphylococcus aureus strain JP02758]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=68513 JP49775_RS13185 WP_000143420.1 2621748..2622635(-) (braS) [Staphylococcus aureus strain JP02758]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGTGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993