Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   JP49775_RS07785 Genome accession   NZ_AP017922
Coordinates   1584107..1585081 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain JP02758     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1579107..1590081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JP49775_RS07745 (JP02758_1472) gcvT 1579608..1580699 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  JP49775_RS07750 (JP02758_1473) - 1580858..1581382 (-) 525 WP_029549655.1 shikimate kinase -
  JP49775_RS07755 - 1581372..1581518 (-) 147 WP_001789879.1 hypothetical protein -
  JP49775_RS07760 (JP02758_1474) comGF 1581615..1582112 (-) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  JP49775_RS07765 (JP02758_1475) comGE 1582030..1582329 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  JP49775_RS07770 (JP02758_1476) comGD 1582316..1582762 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  JP49775_RS07775 (JP02758_1477) comGC 1582740..1583051 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  JP49775_RS07780 (JP02758_1478) comGB 1583065..1584135 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  JP49775_RS07785 (JP02758_1479) comGA 1584107..1585081 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  JP49775_RS07790 (JP02758_1480) - 1585133..1585756 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  JP49775_RS07795 (JP02758_1481) - 1585753..1586082 (-) 330 WP_029549654.1 MTH1187 family thiamine-binding protein -
  JP49775_RS07800 (JP02758_1482) - 1586082..1587068 (-) 987 WP_000161315.1 ROK family glucokinase -
  JP49775_RS07805 (JP02758_1483) - 1587065..1587268 (-) 204 WP_000087559.1 YqgQ family protein -
  JP49775_RS07810 (JP02758_1484) - 1587249..1588712 (-) 1464 WP_001017867.1 rhomboid family protein -
  JP49775_RS07815 (JP02758_1485) - 1588724..1589263 (-) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  JP49775_RS07820 (JP02758_1486) rpmG 1589472..1589621 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=68496 JP49775_RS07785 WP_000697220.1 1584107..1585081(-) (comGA) [Staphylococcus aureus strain JP02758]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=68496 JP49775_RS07785 WP_000697220.1 1584107..1585081(-) (comGA) [Staphylococcus aureus strain JP02758]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment