Detailed information    

insolico Bioinformatically predicted

Overview


Name   comK/comK1   Type   Regulator
Locus tag   JP49775_RS04590 Genome accession   NZ_AP017922
Coordinates   959871..960440 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain JP02758     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context


Location: 954871..965440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JP49775_RS04570 (JP02758_0866) - 956374..957732 (+) 1359 WP_000021872.1 TrkH family potassium uptake protein -
  JP49775_RS04575 (JP02758_0867) - 957871..959382 (+) 1512 WP_033857551.1 bifunctional metallophosphatase/5'-nucleotidase -
  JP49775_RS04590 (JP02758_0868) comK/comK1 959871..960440 (-) 570 WP_000287265.1 competence protein ComK Regulator
  JP49775_RS04595 (JP02758_0869) - 960650..960868 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  JP49775_RS04600 (JP02758_0870) - 960949..961935 (-) 987 WP_000668814.1 lipoate--protein ligase -
  JP49775_RS04605 (JP02758_0871) - 962134..962310 (+) 177 WP_000214898.1 YkvS family protein -
  JP49775_RS04610 (JP02758_0872) - 962325..962927 (+) 603 WP_001033867.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  JP49775_RS14170 - 963242..963304 (+) 63 WP_240785570.1 putative holin-like toxin -
  JP49775_RS04620 (JP02758_0873) - 963939..964223 (+) 285 WP_000790905.1 lactococcin 972 family bacteriocin -

Sequence


Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=68485 JP49775_RS04590 WP_000287265.1 959871..960440(-) (comK/comK1) [Staphylococcus aureus strain JP02758]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=68485 JP49775_RS04590 WP_000287265.1 959871..960440(-) (comK/comK1) [Staphylococcus aureus strain JP02758]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATCAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains


Predicted by InterproScan.

(5-156)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1

  comK/comK1 Staphylococcus aureus N315

100

100

1


Multiple sequence alignment