Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   JP49775_RS02495 Genome accession   NZ_AP017922
Coordinates   531799..532368 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus strain JP02758     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 526799..537368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JP49775_RS02470 (JP02758_0462) cysE 528011..528658 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  JP49775_RS02475 (JP02758_0463) cysS 528642..530042 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  JP49775_RS02480 (JP02758_0464) - 530035..530439 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  JP49775_RS02485 (JP02758_0465) rlmB 530447..531193 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  JP49775_RS02490 (JP02758_0466) - 531193..531717 (+) 525 WP_000664738.1 NYN domain-containing protein -
  JP49775_RS02495 (JP02758_0467) sigH 531799..532368 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  JP49775_RS02500 rpmG 532483..532626 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  JP49775_RS02505 (JP02758_0468) secE 532682..532864 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  JP49775_RS02510 (JP02758_0469) nusG 532877..533425 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  JP49775_RS02515 (JP02758_0470) rplK 533606..534028 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  JP49775_RS02520 (JP02758_0471) rplA 534236..534928 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  JP49775_RS02530 (JP02758_0472) rplJ 535200..535700 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  JP49775_RS02535 (JP02758_0473) rplL 535743..536111 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  JP49775_RS02540 (JP02758_0474) - 536286..536894 (+) 609 WP_000020295.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=68479 JP49775_RS02495 WP_000872879.1 531799..532368(+) (sigH) [Staphylococcus aureus strain JP02758]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=68479 JP49775_RS02495 WP_000872879.1 531799..532368(+) (sigH) [Staphylococcus aureus strain JP02758]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment